di-zhang-fdu/orderly_qa_new · Datasets at Hugging Face

problem stringlengths 128 864	answer stringlengths 1 43
Using CCOC(=O)C(C=O)CCc1ccc(C)nc1, CN(C)Cc1ccnc(CSCCNC(=N)N)c1 to produce Cc1ccc(Cc2cnc(NCCSCc3cc(CN(C)C)ccn3)[nH]c2=O)cn1, please predict the solvent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.	CCO
Using CCOC(=O)C(C=O)CCc1ccc(C)nc1, CN(C)Cc1ccnc(CSCCNC(=N)N)c1 to produce Cc1ccc(Cc2cnc(NCCSCc3cc(CN(C)C)ccn3)[nH]c2=O)cn1, please predict the agent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.	CCO
Using COc1ccc(O)c(C=CC(=O)OC(C)(C)C)c1 to produce COc1ccc(O)c(CCC(=O)OC(C)(C)C)c1, please predict the solvent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.	CO
Using COc1ccc(O)c(C=CC(=O)OC(C)(C)C)c1 to produce COc1ccc(O)c(CCC(=O)OC(C)(C)C)c1, please predict the agent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.	CO
Using O=Cc1cncc(Cl)c1Cl, NO to produce ON=Cc1cncc(Cl)c1Cl, please predict the solvent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.	O, CCO
Using O=Cc1cncc(Cl)c1Cl, NO to produce ON=Cc1cncc(Cl)c1Cl, please predict the agent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.	O, CCO
Using O=Cc1ccc(Oc2ccccc2)cc1, NCC1CC1 to produce c1ccc(Oc2ccc(CNCC3CC3)cc2)cc1, please predict the solvent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.	CO
Using O=Cc1ccc(Oc2ccccc2)cc1, NCC1CC1 to produce c1ccc(Oc2ccc(CNCC3CC3)cc2)cc1, please predict the agent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.	CO
Using CCNC(=O)Nc1nc2cc(-c3cnc(N4CCC(C)(C(=O)OCC)CC4)nc3)cc(NC(=O)c3ncccn3)c2s1 to produce CCNC(=O)Nc1nc2cc(-c3cnc(N4CCC(C)(C(=O)O)CC4)nc3)cc(NC(=O)c3ncccn3)c2s1, please predict the solvent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.	CS(C)=O
Using CCNC(=O)Nc1nc2cc(-c3cnc(N4CCC(C)(C(=O)OCC)CC4)nc3)cc(NC(=O)c3ncccn3)c2s1 to produce CCNC(=O)Nc1nc2cc(-c3cnc(N4CCC(C)(C(=O)O)CC4)nc3)cc(NC(=O)c3ncccn3)c2s1, please predict the agent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.	CS(C)=O
Using O=Cc1cccc2c(Cl)nccc12 to produce OCc1cccc2c(Cl)nccc12, please predict the solvent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.	CO
Using O=Cc1cccc2c(Cl)nccc12 to produce OCc1cccc2c(Cl)nccc12, please predict the agent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.	CO
Using CCNCC, Nc1ncc(/C=C/C=O)c2scc(-c3ccc(Oc4ccccc4)cc3)c12 to produce CCN(CC)C/C=C/c1cnc(N)c2c(-c3ccc(Oc4ccccc4)cc3)csc12, please predict the solvent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.	CC(=O)O, ClCCCl
Using CCNCC, Nc1ncc(/C=C/C=O)c2scc(-c3ccc(Oc4ccccc4)cc3)c12 to produce CCN(CC)C/C=C/c1cnc(N)c2c(-c3ccc(Oc4ccccc4)cc3)csc12, please predict the agent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.	CC(=O)O, ClCCCl
Using COC(=O)C=Cc1ccc2nc(C)n(Cc3ccccc3Cl)c2c1 to produce Cc1nc2ccc(C=CC(=O)O)cc2n1Cc1ccccc1Cl, please predict the solvent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.	CCO
Using COC(=O)C=Cc1ccc2nc(C)n(Cc3ccccc3Cl)c2c1 to produce Cc1nc2ccc(C=CC(=O)O)cc2n1Cc1ccccc1Cl, please predict the agent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.	CCO
Using Nc1ccc(O)cc1[N+](=O)[O-], O=[N+]([O-])c1ccc(F)cc1 to produce Nc1ccc(Oc2ccc([N+](=O)[O-])cc2)cc1[N+](=O)[O-], please predict the solvent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.	CN(C)C=O
Using Nc1ccc(O)cc1[N+](=O)[O-], O=[N+]([O-])c1ccc(F)cc1 to produce Nc1ccc(Oc2ccc([N+](=O)[O-])cc2)cc1[N+](=O)[O-], please predict the agent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.	CN(C)C=O
Using CC(C)(C)[Si](C)(C)ONC(=O)[C@H]1CC[C@H](n2ncc(C(=O)N(CC(=O)c3c(Cl)cncc3Cl)Cc3cc(F)cc(F)c3)c2C(F)(F)F)CC1 to produce O=C(CN(Cc1cc(F)cc(F)c1)C(=O)c1cnn([C@H]2CC[C@H](C(=O)NO)CC2)c1C(F)(F)F)c1c(Cl)cncc1Cl, please predict the solvent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.	C1CCOC1
Using CC(C)(C)[Si](C)(C)ONC(=O)[C@H]1CC[C@H](n2ncc(C(=O)N(CC(=O)c3c(Cl)cncc3Cl)Cc3cc(F)cc(F)c3)c2C(F)(F)F)CC1 to produce O=C(CN(Cc1cc(F)cc(F)c1)C(=O)c1cnn([C@H]2CC[C@H](C(=O)NO)CC2)c1C(F)(F)F)c1c(Cl)cncc1Cl, please predict the agent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.	C1CCOC1
Using COC(=O)COc1cccc(N)c1 to produce C=CCN(CC=C)c1cccc(OCC(=O)OC)c1, please predict the solvent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.	C=CCBr
Using COC(=O)COc1cccc(N)c1 to produce C=CCN(CC=C)c1cccc(OCC(=O)OC)c1, please predict the agent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.	C=CCBr
Using N#CCCCBr, Cc1[nH]cnc1CS to produce Cc1[nH]cnc1CSCCCC#N, please predict the solvent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.	CCO
Using N#CCCCBr, Cc1[nH]cnc1CS to produce Cc1[nH]cnc1CSCCCC#N, please predict the agent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.	CCO
Using CCNC(=O)Nc1nc2cc(-c3cnc(N4CCC(CC)(C(=O)OCC)CC4)nc3)cc(C(=O)CC)c2s1 to produce CCNC(=O)Nc1nc2cc(-c3cnc(N4CCC(CC)(C(=O)O)CC4)nc3)cc(C(=O)CC)c2s1, please predict the solvent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.	CCO
Using CCNC(=O)Nc1nc2cc(-c3cnc(N4CCC(CC)(C(=O)OCC)CC4)nc3)cc(C(=O)CC)c2s1 to produce CCNC(=O)Nc1nc2cc(-c3cnc(N4CCC(CC)(C(=O)O)CC4)nc3)cc(C(=O)CC)c2s1, please predict the agent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.	CCO
Using CCOC(=O)c1cc(-c2nnnn2C)cc([N+](=O)[O-])c1 to produce CCOC(=O)c1cc(N)cc(-c2nnnn2C)c1, please predict the solvent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.	CCOC(C)=O, CCO
Using CCOC(=O)c1cc(-c2nnnn2C)cc([N+](=O)[O-])c1 to produce CCOC(=O)c1cc(N)cc(-c2nnnn2C)c1, please predict the agent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.	CCOC(C)=O, CCO
Using CC(C)n1nc(I)c2c(N)ncnc21, CC(C)(C)OC(=O)n1cc(C=O)c2cc(B3OC(C)(C)C(C)(C)O3)ccc21 to produce CC(C)n1nc(-c2ccc3[nH]cc(C=O)c3c2)c2c(N)ncnc21, please predict the solvent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.	CCO, COCCOC
Using CC(C)n1nc(I)c2c(N)ncnc21, CC(C)(C)OC(=O)n1cc(C=O)c2cc(B3OC(C)(C)C(C)(C)O3)ccc21 to produce CC(C)n1nc(-c2ccc3[nH]cc(C=O)c3c2)c2c(N)ncnc21, please predict the agent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.	CCO, COCCOC
Using CCOC(=O)c1ccc(N(C)CCO[Si](C)(C)C(C)(C)C)cc1 to produce CCOC(=O)c1ccc(N(C)CCO)cc1, please predict the solvent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.	C1CCOC1
Using CCOC(=O)c1ccc(N(C)CCO[Si](C)(C)C(C)(C)C)cc1 to produce CCOC(=O)c1ccc(N(C)CCO)cc1, please predict the agent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.	C1CCOC1
Using [N-]=[N+]=N, OCc1ccccc1C(F)(F)F to produce [N-]=[N+]=NCc1ccccc1C(F)(F)F, please predict the solvent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.	Cc1ccccc1
Using [N-]=[N+]=N, OCc1ccccc1C(F)(F)F to produce [N-]=[N+]=NCc1ccccc1C(F)(F)F, please predict the agent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.	Cc1ccccc1
Using CC(=O)OC[C@H]1O[C@@H](n2cc(I)c(=O)[nH]c2=O)C[C@@H]1F, C#C[Si](C)(C)C to produce CC(=O)OC[C@H]1O[C@@H](n2cc(C#C[Si](C)(C)C)c(=O)[nH]c2=O)C[C@@H]1F, please predict the solvent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.	CCN(CC)CC
Using CC(=O)OC[C@H]1O[C@@H](n2cc(I)c(=O)[nH]c2=O)C[C@@H]1F, C#C[Si](C)(C)C to produce CC(=O)OC[C@H]1O[C@@H](n2cc(C#C[Si](C)(C)C)c(=O)[nH]c2=O)C[C@@H]1F, please predict the agent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.	CCN(CC)CC
Using CC(C)(C)[Si](C)(C)OCCNCc1ccccc1, O=C(O)c1cccnc1Cl to produce CC(C)(C)[Si](C)(C)OCCN(Cc1ccccc1)C(=O)c1cccnc1Cl, please predict the solvent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.	CN(C)C=O, O
Using CC(C)(C)[Si](C)(C)OCCNCc1ccccc1, O=C(O)c1cccnc1Cl to produce CC(C)(C)[Si](C)(C)OCCN(Cc1ccccc1)C(=O)c1cccnc1Cl, please predict the agent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.	CN(C)C=O, O
Using Cn1cncc1C(N)(CCCCOCc1cccc(O)c1)c1ccc(C#N)c(F)c1 to produce Cn1cncc1C1(N)CCCCOCc2cccc(c2)Oc2cc1ccc2C#N, please predict the solvent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.	CN(C)C=O
Using Cn1cncc1C(N)(CCCCOCc1cccc(O)c1)c1ccc(C#N)c(F)c1 to produce Cn1cncc1C1(N)CCCCOCc2cccc(c2)Oc2cc1ccc2C#N, please predict the agent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.	CN(C)C=O
Using Cc1cc(COC2CCCCO2)ccc1Cc1ccccc1 to produce Cc1cc(CO)ccc1Cc1ccccc1, please predict the solvent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.	CO
Using Cc1cc(COC2CCCCO2)ccc1Cc1ccccc1 to produce Cc1cc(CO)ccc1Cc1ccccc1, please predict the agent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.	CO
Using Brc1cccc(Br)c1, CC(=O)n1c2ccccc2c2cc(B3OC(C)(C)C(C)(C)O3)ccc21 to produce CC(=O)n1c2ccccc2c2cc(-c3cccc(Br)c3)ccc21, please predict the solvent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.	O, Cc1ccccc1
Using Brc1cccc(Br)c1, CC(=O)n1c2ccccc2c2cc(B3OC(C)(C)C(C)(C)O3)ccc21 to produce CC(=O)n1c2ccccc2c2cc(-c3cccc(Br)c3)ccc21, please predict the agent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.	O, Cc1ccccc1
Using COC(=O)c1ccc(NC(=O)N2CCCC(C3(Cc4cccc(Cl)c4)C(=O)Nc4cc(Cl)ccc43)C2)cn1 to produce O=C(O)c1ccc(NC(=O)N2CCCC(C3(Cc4cccc(Cl)c4)C(=O)Nc4cc(Cl)ccc43)C2)cn1, please predict the solvent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.	O, C1CCOC1
Using COC(=O)c1ccc(NC(=O)N2CCCC(C3(Cc4cccc(Cl)c4)C(=O)Nc4cc(Cl)ccc43)C2)cn1 to produce O=C(O)c1ccc(NC(=O)N2CCCC(C3(Cc4cccc(Cl)c4)C(=O)Nc4cc(Cl)ccc43)C2)cn1, please predict the agent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.	O, C1CCOC1
Using CC1CCc2c(-c3ccccc3)nc(=O)n(C(C)C)c2C1 to produce Cc1ccc2c(-c3ccccc3)nc(=O)n(C(C)C)c2c1, please predict the solvent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.	Cc1ccccc1C
Using CC1CCc2c(-c3ccccc3)nc(=O)n(C(C)C)c2C1 to produce Cc1ccc2c(-c3ccccc3)nc(=O)n(C(C)C)c2c1, please predict the agent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.	Cc1ccccc1C
Using CCc1cccc2c3c([nH]c12)C(CC)(CC(=O)OC)OCC3=O, CS(=O)(=O)NN to produce CCc1cccc2c3c([nH]c12)C(CC)(CC(=O)OC)OCC3=NNS(C)(=O)=O, please predict the solvent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.	O, CO
Using CCc1cccc2c3c([nH]c12)C(CC)(CC(=O)OC)OCC3=O, CS(=O)(=O)NN to produce CCc1cccc2c3c([nH]c12)C(CC)(CC(=O)OC)OCC3=NNS(C)(=O)=O, please predict the agent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.	O, CO
Using Cc1ccc(S(=O)(=O)OCC(F)(F)F)cc1, COC(=O)c1cc(O)nn1C to produce COC(=O)c1cc(OCC(F)(F)F)nn1C, please predict the solvent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.	CN(C)C=O, O
Using Cc1ccc(S(=O)(=O)OCC(F)(F)F)cc1, COC(=O)c1cc(O)nn1C to produce COC(=O)c1cc(OCC(F)(F)F)nn1C, please predict the agent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.	CN(C)C=O, O
Using CCCc1c(C(=O)OCC)c(C(F)F)nc(C(F)(F)F)c1C(=O)OCC to produce CCCc1c(C(=O)O)cnc(C(F)(F)F)c1C(=O)O, please predict the solvent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.	CO
Using CCCc1c(C(=O)OCC)c(C(F)F)nc(C(F)(F)F)c1C(=O)OCC to produce CCCc1c(C(=O)O)cnc(C(F)(F)F)c1C(=O)O, please predict the agent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.	CO
Using CCNCC, CCOP(=O)(CP(=O)(OCC)OCC)OCC to produce C=C(P(=O)(OCC)OCC)P(=O)(OCC)OCC, please predict the solvent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.	CO
Using CCNCC, CCOP(=O)(CP(=O)(OCC)OCC)OCC to produce C=C(P(=O)(OCC)OCC)P(=O)(OCC)OCC, please predict the agent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.	CO
Using Cc1nnc(-c2cccc(-c3cn(COCC[Si](C)(C)C)c4ncnc(N[C@@H](C)c5nn6ccc(C)c6c(=O)n5-c5ccccc5)c34)c2)o1 to produce Cc1nnc(-c2cccc(-c3c[nH]c4ncnc(N[C@@H](C)c5nn6ccc(C)c6c(=O)n5-c5ccccc5)c34)c2)o1, please predict the solvent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.	O=C(O)C(F)(F)F
Using Cc1nnc(-c2cccc(-c3cn(COCC[Si](C)(C)C)c4ncnc(N[C@@H](C)c5nn6ccc(C)c6c(=O)n5-c5ccccc5)c34)c2)o1 to produce Cc1nnc(-c2cccc(-c3c[nH]c4ncnc(N[C@@H](C)c5nn6ccc(C)c6c(=O)n5-c5ccccc5)c34)c2)o1, please predict the agent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.	O=C(O)C(F)(F)F
Using BrCc1ncccc1Br, [C-]#N to produce N#CCc1ncccc1Br, please predict the solvent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.	C1COCCO1, O
Using BrCc1ncccc1Br, [C-]#N to produce N#CCc1ncccc1Br, please predict the agent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.	C1COCCO1, O
Using C=C(c1ccc(C(=O)OC)cc1)c1ccc2c(c1)C(C)(C)CCC2(C)C to produce C=C(c1ccc(C(=O)O)cc1)c1ccc2c(c1)C(C)(C)CCC2(C)C, please predict the solvent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.	CO
Using C=C(c1ccc(C(=O)OC)cc1)c1ccc2c(c1)C(C)(C)CCC2(C)C to produce C=C(c1ccc(C(=O)O)cc1)c1ccc2c(c1)C(C)(C)CCC2(C)C, please predict the agent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.	CO
Using NC=O, CC(=O)CC1(c2ccc(Cl)cc2)CCC1 to produce CC(N)CC1(c2ccc(Cl)cc2)CCC1, please predict the solvent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.	O=CO, O
Using NC=O, CC(=O)CC1(c2ccc(Cl)cc2)CCC1 to produce CC(N)CC1(c2ccc(Cl)cc2)CCC1, please predict the agent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.	O=CO, O
Using CCOC(=O)n1nc(NC(=O)c2ccc(N3CCN(C)CC3)c([N+](=O)[O-])c2)c2c1CN(S(=O)(=O)c1cccc(F)c1)C2 to produce CCOC(=O)n1nc(NC(=O)c2ccc(N3CCN(C)CC3)c(N)c2)c2c1CN(S(=O)(=O)c1cccc(F)c1)C2, please predict the solvent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.	CCO
Using CCOC(=O)n1nc(NC(=O)c2ccc(N3CCN(C)CC3)c([N+](=O)[O-])c2)c2c1CN(S(=O)(=O)c1cccc(F)c1)C2 to produce CCOC(=O)n1nc(NC(=O)c2ccc(N3CCN(C)CC3)c(N)c2)c2c1CN(S(=O)(=O)c1cccc(F)c1)C2, please predict the agent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.	CCO
Using COC(=O)C1CC2C=CC1O2, CCCCCCCCCCCCCCCCCCN to produce C=CC(=O)NCCCCCCCCCCCCCCCCCC, please predict the solvent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.	O, ClC(Cl)Cl
Using COC(=O)C1CC2C=CC1O2, CCCCCCCCCCCCCCCCCCN to produce C=CC(=O)NCCCCCCCCCCCCCCCCCC, please predict the agent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.	O, ClC(Cl)Cl
Using CCCC(F)(F)C(O)CCC[C@H]1[C@H](C)CC(=O)[C@@H]1C/C=C\CCCC(=O)OC to produce CCCC(F)(F)C(=O)CCC[C@H]1[C@H](C)CC(=O)[C@@H]1C/C=C\CCCC(=O)OC, please predict the solvent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.	ClCCl, c1ccncc1
Using CCCC(F)(F)C(O)CCC[C@H]1[C@H](C)CC(=O)[C@@H]1C/C=C\CCCC(=O)OC to produce CCCC(F)(F)C(=O)CCC[C@H]1[C@H](C)CC(=O)[C@@H]1C/C=C\CCCC(=O)OC, please predict the agent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.	ClCCl, c1ccncc1
Using Cc1ccc(C(N)=O)cc1Br, CC1(C)OB(c2ccc3cc(NC(=O)c4ccsc4)ccc3c2)OC1(C)C to produce Cc1ccc(C(N)=O)cc1-c1ccc2cc(NC(=O)c3ccsc3)ccc2c1, please predict the solvent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.	C1COCCO1, O
Using Cc1ccc(C(N)=O)cc1Br, CC1(C)OB(c2ccc3cc(NC(=O)c4ccsc4)ccc3c2)OC1(C)C to produce Cc1ccc(C(N)=O)cc1-c1ccc2cc(NC(=O)c3ccsc3)ccc2c1, please predict the agent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.	C1COCCO1, O
Using NCCCC[C@H](N)C(=O)O to produce NCCCC[C@H](N)C(=O)[O-], please predict the solvent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.	CCO
Using NCCCC[C@H](N)C(=O)O to produce NCCCC[C@H](N)C(=O)[O-], please predict the agent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.	CCO
Using [C-]#N, O=C(CBr)c1ccc(Br)s1 to produce N#CCC(=O)c1ccc(Br)s1, please predict the solvent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.	CCO
Using [C-]#N, O=C(CBr)c1ccc(Br)s1 to produce N#CCC(=O)c1ccc(Br)s1, please predict the agent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.	CCO
Using CCNC(=O)c1ccc(N=[N+]=[N-])cc1, CCCCC(=O)CC(=O)OC to produce CCCCc1c(C(=O)O)nnn1-c1ccc(C(=O)NCC)cc1, please predict the solvent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.	O, CO
Using CCNC(=O)c1ccc(N=[N+]=[N-])cc1, CCCCC(=O)CC(=O)OC to produce CCCCc1c(C(=O)O)nnn1-c1ccc(C(=O)NCC)cc1, please predict the agent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.	O, CO
Using CCCOc1ccc(CCl)cc1-c1nc2c(CCC)nn(C)c2c(=O)[nH]1 to produce CCCOc1ccc(C)cc1-c1nc2c(CCC)nn(C)c2c(=O)[nH]1, please predict the solvent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.	CCOC(C)=O
Using CCCOc1ccc(CCl)cc1-c1nc2c(CCC)nn(C)c2c(=O)[nH]1 to produce CCCOc1ccc(C)cc1-c1nc2c(CCC)nn(C)c2c(=O)[nH]1, please predict the agent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.	CCOC(C)=O
Using NC(=CC(=O)N1CCn2c(nnc2C(F)(F)F)C1)Cc1cc(F)c(F)cc1F to produce NC(CC(=O)N1CCn2c(nnc2C(F)(F)F)C1)Cc1cc(F)c(F)cc1F, please predict the solvent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.	CC(C)O, C1CCOC1
Using NC(=CC(=O)N1CCn2c(nnc2C(F)(F)F)C1)Cc1cc(F)c(F)cc1F to produce NC(CC(=O)N1CCn2c(nnc2C(F)(F)F)C1)Cc1cc(F)c(F)cc1F, please predict the agent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.	CC(C)O, C1CCOC1
Using Nc1ccc(C(F)(F)F)c2cnccc12, O=C=NCc1ccc(C(F)(F)F)cc1 to produce O=C(NCc1ccc(C(F)(F)F)cc1)Nc1ccc(C(F)(F)F)c2cnccc12, please predict the solvent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.	ClCCl
Using Nc1ccc(C(F)(F)F)c2cnccc12, O=C=NCc1ccc(C(F)(F)F)cc1 to produce O=C(NCc1ccc(C(F)(F)F)cc1)Nc1ccc(C(F)(F)F)c2cnccc12, please predict the agent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.	ClCCl
Using OCCCBr, CC(C)(C)OC(=O)N1CCNCC1 to produce CC(C)(C)OC(=O)N1CCN(CCCO)CC1, please predict the solvent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.	CC(C)=O
Using OCCCBr, CC(C)(C)OC(=O)N1CCNCC1 to produce CC(C)(C)OC(=O)N1CCN(CCCO)CC1, please predict the agent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.	CC(C)=O
Using COC(=O)[C@@H](CC(=O)O)CC1CCCCC1, NCCNc1ccc(F)cc1 to produce COC(=O)[C@@H](CC(=O)NCCNc1ccc(F)cc1)CC1CCCCC1, please predict the solvent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.	ClCCl, CCN(C(C)C)C(C)C
Using COC(=O)[C@@H](CC(=O)O)CC1CCCCC1, NCCNc1ccc(F)cc1 to produce COC(=O)[C@@H](CC(=O)NCCNc1ccc(F)cc1)CC1CCCCC1, please predict the agent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.	ClCCl, CCN(C(C)C)C(C)C
Using CCCCCCCOc1ccc(-n2c(C)ccc2-c2ccc(O[C@H](Cc3ccccc3)C(=O)OCC)cc2)cc1 to produce CCCCCCCOc1ccc(-n2c(C)ccc2-c2ccc(O[C@H](Cc3ccccc3)C(=O)O)cc2)cc1, please predict the solvent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.	C1CCOC1, CO
Using CCCCCCCOc1ccc(-n2c(C)ccc2-c2ccc(O[C@H](Cc3ccccc3)C(=O)OCC)cc2)cc1 to produce CCCCCCCOc1ccc(-n2c(C)ccc2-c2ccc(O[C@H](Cc3ccccc3)C(=O)O)cc2)cc1, please predict the agent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.	C1CCOC1, CO
Using COC(=O)Cc1ccccc1Br, Cc1ccc(C=O)cc1 to produce COC(=O)C(c1ccccc1)C(O)c1ccc(C)cc1, please predict the solvent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.	CCOCC, C1CCOC1
Using COC(=O)Cc1ccccc1Br, Cc1ccc(C=O)cc1 to produce COC(=O)C(c1ccccc1)C(O)c1ccc(C)cc1, please predict the agent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.	CCOCC, C1CCOC1
Using Oc1ccc(Cl)cc1, ClCCCBr to produce ClCCCOc1ccc(Cl)cc1, please predict the solvent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.	O
Using Oc1ccc(Cl)cc1, ClCCCBr to produce ClCCCOc1ccc(Cl)cc1, please predict the agent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.	O
Using COCCN(C)CC[C@H](N)C(=O)OC, CC(C)Cn1ncc2cc(Oc3ccc(F)cc3F)c(C(=O)O)cc21 to produce COCCN(C)CC[C@H](NC(=O)c1cc2c(cnn2CC(C)C)cc1Oc1ccc(F)cc1F)C(=O)OC, please predict the solvent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.	CC(Cl)Cl, CCN(CC)CC
Using COCCN(C)CC[C@H](N)C(=O)OC, CC(C)Cn1ncc2cc(Oc3ccc(F)cc3F)c(C(=O)O)cc21 to produce COCCN(C)CC[C@H](NC(=O)c1cc2c(cnn2CC(C)C)cc1Oc1ccc(F)cc1F)C(=O)OC, please predict the agent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.	CC(Cl)Cl, CCN(CC)CC
Using O=C([O-])[O-], N#Cc1cc(NC(=O)c2cc(Br)ccc2Cl)n(-c2ccccc2)n1 to produce NC(=O)c1cc(NC(=O)c2cc(Br)ccc2Cl)n(-c2ccccc2)n1, please predict the solvent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.	CS(C)=O
Using O=C([O-])[O-], N#Cc1cc(NC(=O)c2cc(Br)ccc2Cl)n(-c2ccccc2)n1 to produce NC(=O)c1cc(NC(=O)c2cc(Br)ccc2Cl)n(-c2ccccc2)n1, please predict the agent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.	CS(C)=O
Using CC(=O)OC(C)=O, O=C(O)c1ccc(O)c(-c2ccccc2)c1 to produce CC(=O)Oc1ccc(C(=O)O)cc1-c1ccccc1, please predict the solvent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.	O
Using CC(=O)OC(C)=O, O=C(O)c1ccc(O)c(-c2ccccc2)c1 to produce CC(=O)Oc1ccc(C(=O)O)cc1-c1ccccc1, please predict the agent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.	O

Using CCOC(=O)C(C=O)CCc1ccc(C)nc1, CN(C)Cc1ccnc(CSCCNC(=N)N)c1 to produce Cc1ccc(Cc2cnc(NCCSCc3cc(CN(C)C)ccn3)[nH]c2=O)cn1, please predict the solvent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.

CCO

Using CCOC(=O)C(C=O)CCc1ccc(C)nc1, CN(C)Cc1ccnc(CSCCNC(=N)N)c1 to produce Cc1ccc(Cc2cnc(NCCSCc3cc(CN(C)C)ccn3)[nH]c2=O)cn1, please predict the agent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.

CCO

Using COc1ccc(O)c(C=CC(=O)OC(C)(C)C)c1 to produce COc1ccc(O)c(CCC(=O)OC(C)(C)C)c1, please predict the solvent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.

CO

Using COc1ccc(O)c(C=CC(=O)OC(C)(C)C)c1 to produce COc1ccc(O)c(CCC(=O)OC(C)(C)C)c1, please predict the agent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.

CO

Using O=Cc1cncc(Cl)c1Cl, NO to produce ON=Cc1cncc(Cl)c1Cl, please predict the solvent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.

O, CCO

Using O=Cc1cncc(Cl)c1Cl, NO to produce ON=Cc1cncc(Cl)c1Cl, please predict the agent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.

O, CCO

Using O=Cc1ccc(Oc2ccccc2)cc1, NCC1CC1 to produce c1ccc(Oc2ccc(CNCC3CC3)cc2)cc1, please predict the solvent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.

CO

Using O=Cc1ccc(Oc2ccccc2)cc1, NCC1CC1 to produce c1ccc(Oc2ccc(CNCC3CC3)cc2)cc1, please predict the agent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.

CO

Using CCNC(=O)Nc1nc2cc(-c3cnc(N4CCC(C)(C(=O)OCC)CC4)nc3)cc(NC(=O)c3ncccn3)c2s1 to produce CCNC(=O)Nc1nc2cc(-c3cnc(N4CCC(C)(C(=O)O)CC4)nc3)cc(NC(=O)c3ncccn3)c2s1, please predict the solvent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.

CS(C)=O

Using CCNC(=O)Nc1nc2cc(-c3cnc(N4CCC(C)(C(=O)OCC)CC4)nc3)cc(NC(=O)c3ncccn3)c2s1 to produce CCNC(=O)Nc1nc2cc(-c3cnc(N4CCC(C)(C(=O)O)CC4)nc3)cc(NC(=O)c3ncccn3)c2s1, please predict the agent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.

CS(C)=O

Using O=Cc1cccc2c(Cl)nccc12 to produce OCc1cccc2c(Cl)nccc12, please predict the solvent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.

CO

Using O=Cc1cccc2c(Cl)nccc12 to produce OCc1cccc2c(Cl)nccc12, please predict the agent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.

CO

Using CCNCC, Nc1ncc(/C=C/C=O)c2scc(-c3ccc(Oc4ccccc4)cc3)c12 to produce CCN(CC)C/C=C/c1cnc(N)c2c(-c3ccc(Oc4ccccc4)cc3)csc12, please predict the solvent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.

CC(=O)O, ClCCCl

Using CCNCC, Nc1ncc(/C=C/C=O)c2scc(-c3ccc(Oc4ccccc4)cc3)c12 to produce CCN(CC)C/C=C/c1cnc(N)c2c(-c3ccc(Oc4ccccc4)cc3)csc12, please predict the agent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.

CC(=O)O, ClCCCl

Using COC(=O)C=Cc1ccc2nc(C)n(Cc3ccccc3Cl)c2c1 to produce Cc1nc2ccc(C=CC(=O)O)cc2n1Cc1ccccc1Cl, please predict the solvent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.

CCO

Using COC(=O)C=Cc1ccc2nc(C)n(Cc3ccccc3Cl)c2c1 to produce Cc1nc2ccc(C=CC(=O)O)cc2n1Cc1ccccc1Cl, please predict the agent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.

CCO

Using Nc1ccc(O)cc1[N+](=O)[O-], O=[N+]([O-])c1ccc(F)cc1 to produce Nc1ccc(Oc2ccc([N+](=O)[O-])cc2)cc1[N+](=O)[O-], please predict the solvent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.

CN(C)C=O

Using Nc1ccc(O)cc1[N+](=O)[O-], O=[N+]([O-])c1ccc(F)cc1 to produce Nc1ccc(Oc2ccc([N+](=O)[O-])cc2)cc1[N+](=O)[O-], please predict the agent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.

CN(C)C=O

Using CC(C)(C)[Si](C)(C)ONC(=O)[C@H]1CC[C@H](n2ncc(C(=O)N(CC(=O)c3c(Cl)cncc3Cl)Cc3cc(F)cc(F)c3)c2C(F)(F)F)CC1 to produce O=C(CN(Cc1cc(F)cc(F)c1)C(=O)c1cnn([C@H]2CC[C@H](C(=O)NO)CC2)c1C(F)(F)F)c1c(Cl)cncc1Cl, please predict the solvent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.

C1CCOC1

Using CC(C)(C)[Si](C)(C)ONC(=O)[C@H]1CC[C@H](n2ncc(C(=O)N(CC(=O)c3c(Cl)cncc3Cl)Cc3cc(F)cc(F)c3)c2C(F)(F)F)CC1 to produce O=C(CN(Cc1cc(F)cc(F)c1)C(=O)c1cnn([C@H]2CC[C@H](C(=O)NO)CC2)c1C(F)(F)F)c1c(Cl)cncc1Cl, please predict the agent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.

C1CCOC1

Using COC(=O)COc1cccc(N)c1 to produce C=CCN(CC=C)c1cccc(OCC(=O)OC)c1, please predict the solvent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.

C=CCBr

Using COC(=O)COc1cccc(N)c1 to produce C=CCN(CC=C)c1cccc(OCC(=O)OC)c1, please predict the agent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.

C=CCBr

Using N#CCCCBr, Cc1[nH]cnc1CS to produce Cc1[nH]cnc1CSCCCC#N, please predict the solvent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.

CCO

Using N#CCCCBr, Cc1[nH]cnc1CS to produce Cc1[nH]cnc1CSCCCC#N, please predict the agent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.

CCO

Using CCNC(=O)Nc1nc2cc(-c3cnc(N4CCC(CC)(C(=O)OCC)CC4)nc3)cc(C(=O)CC)c2s1 to produce CCNC(=O)Nc1nc2cc(-c3cnc(N4CCC(CC)(C(=O)O)CC4)nc3)cc(C(=O)CC)c2s1, please predict the solvent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.

CCO

Using CCNC(=O)Nc1nc2cc(-c3cnc(N4CCC(CC)(C(=O)OCC)CC4)nc3)cc(C(=O)CC)c2s1 to produce CCNC(=O)Nc1nc2cc(-c3cnc(N4CCC(CC)(C(=O)O)CC4)nc3)cc(C(=O)CC)c2s1, please predict the agent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.

CCO

Using CCOC(=O)c1cc(-c2nnnn2C)cc([N+](=O)[O-])c1 to produce CCOC(=O)c1cc(N)cc(-c2nnnn2C)c1, please predict the solvent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.

CCOC(C)=O, CCO

Using CCOC(=O)c1cc(-c2nnnn2C)cc([N+](=O)[O-])c1 to produce CCOC(=O)c1cc(N)cc(-c2nnnn2C)c1, please predict the agent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.

CCOC(C)=O, CCO

Using CC(C)n1nc(I)c2c(N)ncnc21, CC(C)(C)OC(=O)n1cc(C=O)c2cc(B3OC(C)(C)C(C)(C)O3)ccc21 to produce CC(C)n1nc(-c2ccc3[nH]cc(C=O)c3c2)c2c(N)ncnc21, please predict the solvent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.

CCO, COCCOC

Using CC(C)n1nc(I)c2c(N)ncnc21, CC(C)(C)OC(=O)n1cc(C=O)c2cc(B3OC(C)(C)C(C)(C)O3)ccc21 to produce CC(C)n1nc(-c2ccc3[nH]cc(C=O)c3c2)c2c(N)ncnc21, please predict the agent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.

CCO, COCCOC

Using CCOC(=O)c1ccc(N(C)CCO[Si](C)(C)C(C)(C)C)cc1 to produce CCOC(=O)c1ccc(N(C)CCO)cc1, please predict the solvent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.

C1CCOC1

Using CCOC(=O)c1ccc(N(C)CCO[Si](C)(C)C(C)(C)C)cc1 to produce CCOC(=O)c1ccc(N(C)CCO)cc1, please predict the agent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.

C1CCOC1

Using [N-]=[N+]=N, OCc1ccccc1C(F)(F)F to produce [N-]=[N+]=NCc1ccccc1C(F)(F)F, please predict the solvent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.

Cc1ccccc1

Using [N-]=[N+]=N, OCc1ccccc1C(F)(F)F to produce [N-]=[N+]=NCc1ccccc1C(F)(F)F, please predict the agent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.

Cc1ccccc1

Using CC(=O)OC[C@H]1O[C@@H](n2cc(I)c(=O)[nH]c2=O)C[C@@H]1F, C#C[Si](C)(C)C to produce CC(=O)OC[C@H]1O[C@@H](n2cc(C#C[Si](C)(C)C)c(=O)[nH]c2=O)C[C@@H]1F, please predict the solvent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.

CCN(CC)CC

Using CC(=O)OC[C@H]1O[C@@H](n2cc(I)c(=O)[nH]c2=O)C[C@@H]1F, C#C[Si](C)(C)C to produce CC(=O)OC[C@H]1O[C@@H](n2cc(C#C[Si](C)(C)C)c(=O)[nH]c2=O)C[C@@H]1F, please predict the agent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.

CCN(CC)CC

Using CC(C)(C)[Si](C)(C)OCCNCc1ccccc1, O=C(O)c1cccnc1Cl to produce CC(C)(C)[Si](C)(C)OCCN(Cc1ccccc1)C(=O)c1cccnc1Cl, please predict the solvent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.

CN(C)C=O, O

Using CC(C)(C)[Si](C)(C)OCCNCc1ccccc1, O=C(O)c1cccnc1Cl to produce CC(C)(C)[Si](C)(C)OCCN(Cc1ccccc1)C(=O)c1cccnc1Cl, please predict the agent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.

CN(C)C=O, O

Using Cn1cncc1C(N)(CCCCOCc1cccc(O)c1)c1ccc(C#N)c(F)c1 to produce Cn1cncc1C1(N)CCCCOCc2cccc(c2)Oc2cc1ccc2C#N, please predict the solvent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.

CN(C)C=O

Using Cn1cncc1C(N)(CCCCOCc1cccc(O)c1)c1ccc(C#N)c(F)c1 to produce Cn1cncc1C1(N)CCCCOCc2cccc(c2)Oc2cc1ccc2C#N, please predict the agent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.

CN(C)C=O

Using Cc1cc(COC2CCCCO2)ccc1Cc1ccccc1 to produce Cc1cc(CO)ccc1Cc1ccccc1, please predict the solvent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.

CO

Using Cc1cc(COC2CCCCO2)ccc1Cc1ccccc1 to produce Cc1cc(CO)ccc1Cc1ccccc1, please predict the agent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.

CO

Using Brc1cccc(Br)c1, CC(=O)n1c2ccccc2c2cc(B3OC(C)(C)C(C)(C)O3)ccc21 to produce CC(=O)n1c2ccccc2c2cc(-c3cccc(Br)c3)ccc21, please predict the solvent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.

O, Cc1ccccc1

Using Brc1cccc(Br)c1, CC(=O)n1c2ccccc2c2cc(B3OC(C)(C)C(C)(C)O3)ccc21 to produce CC(=O)n1c2ccccc2c2cc(-c3cccc(Br)c3)ccc21, please predict the agent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.

O, Cc1ccccc1

Using COC(=O)c1ccc(NC(=O)N2CCCC(C3(Cc4cccc(Cl)c4)C(=O)Nc4cc(Cl)ccc43)C2)cn1 to produce O=C(O)c1ccc(NC(=O)N2CCCC(C3(Cc4cccc(Cl)c4)C(=O)Nc4cc(Cl)ccc43)C2)cn1, please predict the solvent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.

O, C1CCOC1

Using COC(=O)c1ccc(NC(=O)N2CCCC(C3(Cc4cccc(Cl)c4)C(=O)Nc4cc(Cl)ccc43)C2)cn1 to produce O=C(O)c1ccc(NC(=O)N2CCCC(C3(Cc4cccc(Cl)c4)C(=O)Nc4cc(Cl)ccc43)C2)cn1, please predict the agent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.

O, C1CCOC1

Using CC1CCc2c(-c3ccccc3)nc(=O)n(C(C)C)c2C1 to produce Cc1ccc2c(-c3ccccc3)nc(=O)n(C(C)C)c2c1, please predict the solvent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.

Cc1ccccc1C

Using CC1CCc2c(-c3ccccc3)nc(=O)n(C(C)C)c2C1 to produce Cc1ccc2c(-c3ccccc3)nc(=O)n(C(C)C)c2c1, please predict the agent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.

Cc1ccccc1C

Using CCc1cccc2c3c([nH]c12)C(CC)(CC(=O)OC)OCC3=O, CS(=O)(=O)NN to produce CCc1cccc2c3c([nH]c12)C(CC)(CC(=O)OC)OCC3=NNS(C)(=O)=O, please predict the solvent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.

O, CO

Using CCc1cccc2c3c([nH]c12)C(CC)(CC(=O)OC)OCC3=O, CS(=O)(=O)NN to produce CCc1cccc2c3c([nH]c12)C(CC)(CC(=O)OC)OCC3=NNS(C)(=O)=O, please predict the agent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.

O, CO

Using Cc1ccc(S(=O)(=O)OCC(F)(F)F)cc1, COC(=O)c1cc(O)nn1C to produce COC(=O)c1cc(OCC(F)(F)F)nn1C, please predict the solvent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.

CN(C)C=O, O

Using Cc1ccc(S(=O)(=O)OCC(F)(F)F)cc1, COC(=O)c1cc(O)nn1C to produce COC(=O)c1cc(OCC(F)(F)F)nn1C, please predict the agent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.

CN(C)C=O, O

Using CCCc1c(C(=O)OCC)c(C(F)F)nc(C(F)(F)F)c1C(=O)OCC to produce CCCc1c(C(=O)O)cnc(C(F)(F)F)c1C(=O)O, please predict the solvent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.

CO

Using CCCc1c(C(=O)OCC)c(C(F)F)nc(C(F)(F)F)c1C(=O)OCC to produce CCCc1c(C(=O)O)cnc(C(F)(F)F)c1C(=O)O, please predict the agent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.

CO

Using CCNCC, CCOP(=O)(CP(=O)(OCC)OCC)OCC to produce C=C(P(=O)(OCC)OCC)P(=O)(OCC)OCC, please predict the solvent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.

CO

Using CCNCC, CCOP(=O)(CP(=O)(OCC)OCC)OCC to produce C=C(P(=O)(OCC)OCC)P(=O)(OCC)OCC, please predict the agent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.

CO

Using Cc1nnc(-c2cccc(-c3cn(COCC[Si](C)(C)C)c4ncnc(N[C@@H](C)c5nn6ccc(C)c6c(=O)n5-c5ccccc5)c34)c2)o1 to produce Cc1nnc(-c2cccc(-c3c[nH]c4ncnc(N[C@@H](C)c5nn6ccc(C)c6c(=O)n5-c5ccccc5)c34)c2)o1, please predict the solvent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.

O=C(O)C(F)(F)F

Using Cc1nnc(-c2cccc(-c3cn(COCC[Si](C)(C)C)c4ncnc(N[C@@H](C)c5nn6ccc(C)c6c(=O)n5-c5ccccc5)c34)c2)o1 to produce Cc1nnc(-c2cccc(-c3c[nH]c4ncnc(N[C@@H](C)c5nn6ccc(C)c6c(=O)n5-c5ccccc5)c34)c2)o1, please predict the agent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.

O=C(O)C(F)(F)F

Using BrCc1ncccc1Br, [C-]#N to produce N#CCc1ncccc1Br, please predict the solvent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.

C1COCCO1, O

Using BrCc1ncccc1Br, [C-]#N to produce N#CCc1ncccc1Br, please predict the agent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.

C1COCCO1, O

Using C=C(c1ccc(C(=O)OC)cc1)c1ccc2c(c1)C(C)(C)CCC2(C)C to produce C=C(c1ccc(C(=O)O)cc1)c1ccc2c(c1)C(C)(C)CCC2(C)C, please predict the solvent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.

CO

Using C=C(c1ccc(C(=O)OC)cc1)c1ccc2c(c1)C(C)(C)CCC2(C)C to produce C=C(c1ccc(C(=O)O)cc1)c1ccc2c(c1)C(C)(C)CCC2(C)C, please predict the agent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.

CO

Using NC=O, CC(=O)CC1(c2ccc(Cl)cc2)CCC1 to produce CC(N)CC1(c2ccc(Cl)cc2)CCC1, please predict the solvent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.

O=CO, O

Using NC=O, CC(=O)CC1(c2ccc(Cl)cc2)CCC1 to produce CC(N)CC1(c2ccc(Cl)cc2)CCC1, please predict the agent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.

O=CO, O

Using CCOC(=O)n1nc(NC(=O)c2ccc(N3CCN(C)CC3)c([N+](=O)[O-])c2)c2c1CN(S(=O)(=O)c1cccc(F)c1)C2 to produce CCOC(=O)n1nc(NC(=O)c2ccc(N3CCN(C)CC3)c(N)c2)c2c1CN(S(=O)(=O)c1cccc(F)c1)C2, please predict the solvent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.

CCO

Using CCOC(=O)n1nc(NC(=O)c2ccc(N3CCN(C)CC3)c([N+](=O)[O-])c2)c2c1CN(S(=O)(=O)c1cccc(F)c1)C2 to produce CCOC(=O)n1nc(NC(=O)c2ccc(N3CCN(C)CC3)c(N)c2)c2c1CN(S(=O)(=O)c1cccc(F)c1)C2, please predict the agent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.

CCO

Using COC(=O)C1CC2C=CC1O2, CCCCCCCCCCCCCCCCCCN to produce C=CC(=O)NCCCCCCCCCCCCCCCCCC, please predict the solvent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.

O, ClC(Cl)Cl

Using COC(=O)C1CC2C=CC1O2, CCCCCCCCCCCCCCCCCCN to produce C=CC(=O)NCCCCCCCCCCCCCCCCCC, please predict the agent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.

O, ClC(Cl)Cl

Using CCCC(F)(F)C(O)CCC[C@H]1[C@H](C)CC(=O)[C@@H]1C/C=C\CCCC(=O)OC to produce CCCC(F)(F)C(=O)CCC[C@H]1[C@H](C)CC(=O)[C@@H]1C/C=C\CCCC(=O)OC, please predict the solvent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.

ClCCl, c1ccncc1

Using CCCC(F)(F)C(O)CCC[C@H]1[C@H](C)CC(=O)[C@@H]1C/C=C\CCCC(=O)OC to produce CCCC(F)(F)C(=O)CCC[C@H]1[C@H](C)CC(=O)[C@@H]1C/C=C\CCCC(=O)OC, please predict the agent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.

ClCCl, c1ccncc1

Using Cc1ccc(C(N)=O)cc1Br, CC1(C)OB(c2ccc3cc(NC(=O)c4ccsc4)ccc3c2)OC1(C)C to produce Cc1ccc(C(N)=O)cc1-c1ccc2cc(NC(=O)c3ccsc3)ccc2c1, please predict the solvent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.

C1COCCO1, O

Using Cc1ccc(C(N)=O)cc1Br, CC1(C)OB(c2ccc3cc(NC(=O)c4ccsc4)ccc3c2)OC1(C)C to produce Cc1ccc(C(N)=O)cc1-c1ccc2cc(NC(=O)c3ccsc3)ccc2c1, please predict the agent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.

C1COCCO1, O

Using NCCCC[C@H](N)C(=O)O to produce NCCCC[C@H](N)C(=O)[O-], please predict the solvent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.

CCO

Using NCCCC[C@H](N)C(=O)O to produce NCCCC[C@H](N)C(=O)[O-], please predict the agent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.

CCO

Using [C-]#N, O=C(CBr)c1ccc(Br)s1 to produce N#CCC(=O)c1ccc(Br)s1, please predict the solvent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.

CCO

Using [C-]#N, O=C(CBr)c1ccc(Br)s1 to produce N#CCC(=O)c1ccc(Br)s1, please predict the agent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.

CCO

Using CCNC(=O)c1ccc(N=[N+]=[N-])cc1, CCCCC(=O)CC(=O)OC to produce CCCCc1c(C(=O)O)nnn1-c1ccc(C(=O)NCC)cc1, please predict the solvent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.

O, CO

Using CCNC(=O)c1ccc(N=[N+]=[N-])cc1, CCCCC(=O)CC(=O)OC to produce CCCCc1c(C(=O)O)nnn1-c1ccc(C(=O)NCC)cc1, please predict the agent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.

O, CO

Using CCCOc1ccc(CCl)cc1-c1nc2c(CCC)nn(C)c2c(=O)[nH]1 to produce CCCOc1ccc(C)cc1-c1nc2c(CCC)nn(C)c2c(=O)[nH]1, please predict the solvent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.

CCOC(C)=O

Using CCCOc1ccc(CCl)cc1-c1nc2c(CCC)nn(C)c2c(=O)[nH]1 to produce CCCOc1ccc(C)cc1-c1nc2c(CCC)nn(C)c2c(=O)[nH]1, please predict the agent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.

CCOC(C)=O

Using NC(=CC(=O)N1CCn2c(nnc2C(F)(F)F)C1)Cc1cc(F)c(F)cc1F to produce NC(CC(=O)N1CCn2c(nnc2C(F)(F)F)C1)Cc1cc(F)c(F)cc1F, please predict the solvent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.

CC(C)O, C1CCOC1

Using NC(=CC(=O)N1CCn2c(nnc2C(F)(F)F)C1)Cc1cc(F)c(F)cc1F to produce NC(CC(=O)N1CCn2c(nnc2C(F)(F)F)C1)Cc1cc(F)c(F)cc1F, please predict the agent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.

CC(C)O, C1CCOC1

Using Nc1ccc(C(F)(F)F)c2cnccc12, O=C=NCc1ccc(C(F)(F)F)cc1 to produce O=C(NCc1ccc(C(F)(F)F)cc1)Nc1ccc(C(F)(F)F)c2cnccc12, please predict the solvent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.

ClCCl

Using Nc1ccc(C(F)(F)F)c2cnccc12, O=C=NCc1ccc(C(F)(F)F)cc1 to produce O=C(NCc1ccc(C(F)(F)F)cc1)Nc1ccc(C(F)(F)F)c2cnccc12, please predict the agent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.

ClCCl

Using OCCCBr, CC(C)(C)OC(=O)N1CCNCC1 to produce CC(C)(C)OC(=O)N1CCN(CCCO)CC1, please predict the solvent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.

CC(C)=O

Using OCCCBr, CC(C)(C)OC(=O)N1CCNCC1 to produce CC(C)(C)OC(=O)N1CCN(CCCO)CC1, please predict the agent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.

CC(C)=O

Using COC(=O)[C@@H](CC(=O)O)CC1CCCCC1, NCCNc1ccc(F)cc1 to produce COC(=O)[C@@H](CC(=O)NCCNc1ccc(F)cc1)CC1CCCCC1, please predict the solvent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.

ClCCl, CCN(C(C)C)C(C)C

Using COC(=O)[C@@H](CC(=O)O)CC1CCCCC1, NCCNc1ccc(F)cc1 to produce COC(=O)[C@@H](CC(=O)NCCNc1ccc(F)cc1)CC1CCCCC1, please predict the agent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.

ClCCl, CCN(C(C)C)C(C)C

Using CCCCCCCOc1ccc(-n2c(C)ccc2-c2ccc(O[C@H](Cc3ccccc3)C(=O)OCC)cc2)cc1 to produce CCCCCCCOc1ccc(-n2c(C)ccc2-c2ccc(O[C@H](Cc3ccccc3)C(=O)O)cc2)cc1, please predict the solvent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.

C1CCOC1, CO

Using CCCCCCCOc1ccc(-n2c(C)ccc2-c2ccc(O[C@H](Cc3ccccc3)C(=O)OCC)cc2)cc1 to produce CCCCCCCOc1ccc(-n2c(C)ccc2-c2ccc(O[C@H](Cc3ccccc3)C(=O)O)cc2)cc1, please predict the agent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.

C1CCOC1, CO

Using COC(=O)Cc1ccccc1Br, Cc1ccc(C=O)cc1 to produce COC(=O)C(c1ccccc1)C(O)c1ccc(C)cc1, please predict the solvent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.

CCOCC, C1CCOC1

Using COC(=O)Cc1ccccc1Br, Cc1ccc(C=O)cc1 to produce COC(=O)C(c1ccccc1)C(O)c1ccc(C)cc1, please predict the agent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.

CCOCC, C1CCOC1

Using Oc1ccc(Cl)cc1, ClCCCBr to produce ClCCCOc1ccc(Cl)cc1, please predict the solvent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.

O

Using Oc1ccc(Cl)cc1, ClCCCBr to produce ClCCCOc1ccc(Cl)cc1, please predict the agent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.

O

Using COCCN(C)CC[C@H](N)C(=O)OC, CC(C)Cn1ncc2cc(Oc3ccc(F)cc3F)c(C(=O)O)cc21 to produce COCCN(C)CC[C@H](NC(=O)c1cc2c(cnn2CC(C)C)cc1Oc1ccc(F)cc1F)C(=O)OC, please predict the solvent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.

CC(Cl)Cl, CCN(CC)CC

Using COCCN(C)CC[C@H](N)C(=O)OC, CC(C)Cn1ncc2cc(Oc3ccc(F)cc3F)c(C(=O)O)cc21 to produce COCCN(C)CC[C@H](NC(=O)c1cc2c(cnn2CC(C)C)cc1Oc1ccc(F)cc1F)C(=O)OC, please predict the agent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.

CC(Cl)Cl, CCN(CC)CC

Using O=C([O-])[O-], N#Cc1cc(NC(=O)c2cc(Br)ccc2Cl)n(-c2ccccc2)n1 to produce NC(=O)c1cc(NC(=O)c2cc(Br)ccc2Cl)n(-c2ccccc2)n1, please predict the solvent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.

CS(C)=O

Using O=C([O-])[O-], N#Cc1cc(NC(=O)c2cc(Br)ccc2Cl)n(-c2ccccc2)n1 to produce NC(=O)c1cc(NC(=O)c2cc(Br)ccc2Cl)n(-c2ccccc2)n1, please predict the agent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.

CS(C)=O

Using CC(=O)OC(C)=O, O=C(O)c1ccc(O)c(-c2ccccc2)c1 to produce CC(=O)Oc1ccc(C(=O)O)cc1-c1ccccc1, please predict the solvent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.

O

Using CC(=O)OC(C)=O, O=C(O)c1ccc(O)c(-c2ccccc2)c1 to produce CC(=O)Oc1ccc(C(=O)O)cc1-c1ccccc1, please predict the agent for this reaction in SMILES notation in \boxed{$SMILES1, SMILES2, ...} format.

O