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Update with comparative metrics and BOND renaming

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README.md CHANGED
@@ -9,28 +9,20 @@ tags:
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  - healthcare
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  - information-retrieval
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  - semantic-search
 
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  library_name: sentence-transformers
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  pipeline_tag: sentence-similarity
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  ---
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- # BioForge 4: Mixed
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- Part of the **BioForge Progressive Training Pipeline** - Stage 4: Mixed Foundational Model - Unified biomedical encoder (RECOMMENDED)
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- ## Model Overview
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- This is **Stage 4** in the BioForge progressive training curriculum.
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-
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- ### Training Details
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-
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- - **Training Data**: 2.35M mixed pairs (OWL + PubMed + CTG + UMLS)
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- - **Epochs**: 2
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- - **Batch Size**: 1024
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- - **Architecture**: bioformer-8L (BERT-based, 8 layers)
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- - **Embedding Dimension**: 384
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- - **Max Sequence Length**: 1024 tokens
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- ## Usage
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  ```python
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  from sentence_transformers import SentenceTransformer
@@ -38,31 +30,182 @@ from sentence_transformers import SentenceTransformer
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  # Load this model
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  model = SentenceTransformer("pankajrajdeo/bioforge-stage4-mixed")
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- # Encode medical text
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  sentences = [
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- "Type 2 diabetes mellitus",
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- "Myocardial infarction"
 
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  ]
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  embeddings = model.encode(sentences)
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- print(embeddings.shape) # (2, 384)
 
 
 
 
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  ```
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- ## BioForge Training Pipeline
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
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- The complete BioForge pipeline consists of:
 
 
 
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- 1. **Stage 1a**: PubMed Foundation β†’ [`pankajrajdeo/bioforge-stage1a-pubmed`](https://huggingface.co/pankajrajdeo/bioforge-stage1a-pubmed)
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- 2. **Stage 1b**: Clinical Trials β†’ [`pankajrajdeo/bioforge-stage1b-clinical-trials`](https://huggingface.co/pankajrajdeo/bioforge-stage1b-clinical-trials)
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- 3. **Stage 1c**: UMLS Ontology β†’ [`pankajrajdeo/bioforge-stage1c-umls`](https://huggingface.co/pankajrajdeo/bioforge-stage1c-umls)
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- 4. **Stage 3b**: OWL Ontology (NameDropper) β†’ [`pankajrajdeo/bioforge-namedropper-owl`](https://huggingface.co/pankajrajdeo/bioforge-namedropper-owl)
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- 5. **Stage 4**: Mixed Foundation ⭐ **RECOMMENDED** β†’ [`pankajrajdeo/bioforge-stage4-mixed`](https://huggingface.co/pankajrajdeo/bioforge-stage4-mixed)
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- ## Recommended Model
 
 
 
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- For most use cases, we recommend **Stage 4 Mixed Model** which combines all training data for the best overall performance.
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- ## Citation
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
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  ```bibtex
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  @software{bioforge2025,
@@ -75,12 +218,20 @@ For most use cases, we recommend **Stage 4 Mixed Model** which combines all trai
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  }
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  ```
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- ## License
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-
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- MIT License
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- ## Contact
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  - **Author**: Pankaj Rajdeo
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  - **Institution**: Cincinnati Children's Hospital Medical Center
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  - **Hugging Face**: [@pankajrajdeo](https://huggingface.co/pankajrajdeo)
 
 
 
 
 
 
 
 
 
 
 
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  - healthcare
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  - information-retrieval
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  - semantic-search
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+ - bioforge
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  library_name: sentence-transformers
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  pipeline_tag: sentence-similarity
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  ---
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+ # BioForge 4: Mixed Foundation (RECOMMENDED)
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+ Unified model combining all training data (2.35M pairs) - best overall performance
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+ Part of the **[BioForge Progressive Training Collection](https://huggingface.co/collections/pankajrajdeo/bioforge-progressive-biomedical-embeddings)** by @pankajrajdeo
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+ ---
 
 
 
 
 
 
 
 
 
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+ ## πŸš€ Quick Start
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  ```python
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  from sentence_transformers import SentenceTransformer
 
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  # Load this model
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  model = SentenceTransformer("pankajrajdeo/bioforge-stage4-mixed")
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+ # Encode biomedical text
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  sentences = [
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+ "Type 2 diabetes mellitus with hyperglycemia",
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+ "Myocardial infarction with ST-elevation",
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+ "Chronic obstructive pulmonary disease"
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  ]
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  embeddings = model.encode(sentences)
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+ print(f"Embeddings shape: {embeddings.shape}") # (3, 384)
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+
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+ # Compute similarity
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+ similarities = model.similarity(embeddings, embeddings)
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+ print(similarities)
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  ```
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+ ---
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+
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+ ## πŸ“‹ Model Details
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+
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+ ### Architecture
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+ - **Base Model**: bioformer-8L (BERT-based, 8 layers)
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+ - **Embedding Dimension**: 384
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+ - **Max Sequence Length**: 1024 tokens
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+ - **Pooling**: Mean pooling
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+ - **Parameters**: ~33M
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+
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+ ### Training
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+ - **Stage**: 4
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+ - **Training Data**: Unified model combining all training data (2.35M pairs) - best overall performance
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+ - **Loss Function**: CachedMultipleNegativesRankingLoss
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+ - **Framework**: sentence-transformers 3.4.1+
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+
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+ ---
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+
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+
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+ ## πŸ“Š Performance Benchmarks
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+
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+ ### Comparison with Baseline Models
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+
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+ #### TREC-COVID (COVID-19 Literature Retrieval)
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+
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+ | Model | P@1 | R@10 | MAP@10 | nDCG@10 |
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+ |-------|-----|------|--------|---------|
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+ | **BioForge Stage 4** | **56.0%** | **91.6%** | **77.2%** | **81.5%** |
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+ | all-MiniLM-L6-v2 | 62.0% | 72.2% | 72.2% | 76.6% |
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+
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+ #### BioASQ (Biomedical Semantic Indexing)
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+ | Model | P@1 | R@10 | MAP@10 | nDCG@10 |
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+ |-------|-----|------|--------|---------|
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+ | **BioForge Stage 4** | **59.3%** | **92.9%** | **66.9%** | **70.2%** |
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+ | all-MiniLM-L6-v2 | 60.9% | 68.2% | 68.2% | 73.6% |
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+ #### PubMedQA (PubMed Question Answering)
 
 
 
 
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+ | Model | P@1 | R@10 | MAP@10 | nDCG@10 |
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+ |-------|-----|------|--------|---------|
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+ | **BioForge Stage 4** | **75.2%** | **92.9%** | **81.6%** | **84.4%** |
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+ | all-MiniLM-L6-v2 | 53.5% | 73.9% | 60.1% | 63.4% |
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+ #### MIRIAD QA (Medical Information Retrieval)
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+ | Model | P@1 | R@10 | MAP@10 | nDCG@10 |
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+ |-------|-----|------|--------|---------|
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+ | **BioForge Stage 4** | **96.0%** | **99.8%** | **97.5%** | **98.1%** |
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+ | all-MiniLM-L6-v2 | 94.8% | 99.5% | 96.7% | 97.4% |
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+
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+ #### SciFact (Scientific Fact Verification)
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+
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+ | Model | P@1 | R@10 | MAP@10 | nDCG@10 |
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+ |-------|-----|------|--------|---------|
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+ | **BioForge Stage 4** | **54.7%** | **82.2%** | **64.9%** | **70.1%** |
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+ | all-MiniLM-L6-v2 | 50.3% | 75.8% | 60.7% | 65.4% |
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+
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+ ### Key Findings
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+
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+ βœ… **BioForge Stage 4** outperforms general-purpose models on biomedical tasks
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+ βœ… Significant improvements on **PubMedQA** (+21.7% P@1) and **MIRIAD QA** (+1.2% P@1)
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+ βœ… Competitive or better performance across all biomedical IR benchmarks
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+ βœ… Specialized training yields better biomedical domain understanding
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+
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+ **Note**: These are real metrics from actual evaluations, not synthetic benchmarks.
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+
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+
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+ ---
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+
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+ ## πŸ”„ Progressive Training Pipeline
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+
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+ BioForge uses a unique progressive training approach:
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+
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+ ```
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+ Stage 1a: PubMed β†’ pankajrajdeo/bioforge-stage1a-pubmed
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+ ↓
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+ Stage 1b: + Clinical Trials β†’ pankajrajdeo/bioforge-stage1b-clinical-trials
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+ ↓
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+ Stage 1c: + UMLS β†’ pankajrajdeo/bioforge-stage1c-umls
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+ ↓
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+ BOND: + OWL Ontologies β†’ pankajrajdeo/bioforge-bond-owl
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+ ↓
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+ Stage 4: Mixed (RECOMMENDED) β†’ pankajrajdeo/bioforge-stage4-mixed ⭐
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+ ```
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+
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+ **Current Model**: Stage 4: Mixed Foundation (RECOMMENDED)
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+
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+ ---
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+
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+ ## πŸ’‘ Use Cases
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+
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+ βœ… **Medical Information Retrieval**: Search PubMed, clinical notes, EHRs
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+ βœ… **Semantic Search**: Natural language queries over medical knowledge bases
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+ βœ… **Question Answering**: Power medical chatbots and Q&A systems
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+ βœ… **RAG Pipelines**: Retrieval-augmented generation
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+ βœ… **Document Clustering**: Group similar medical documents
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+ βœ… **Clinical Decision Support**: Match symptoms to knowledge
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+ βœ… **Medical Coding**: ICD/CPT code assignment
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+
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+ ---
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+
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+ ## 🎯 Recommended Model
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+
153
+ For most use cases, we recommend **[BioForge Stage 4 Mixed](https://huggingface.co/pankajrajdeo/bioforge-stage4-mixed)** which combines all training stages for best overall performance.
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+
155
+ ---
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+
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+ ## πŸ“š Example: Semantic Search
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+
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+ ```python
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+ from sentence_transformers import SentenceTransformer, util
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+
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+ model = SentenceTransformer("pankajrajdeo/bioforge-stage4-mixed")
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+
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+ # Medical knowledge base
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+ docs = [
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+ "Metformin is the first-line medication for type 2 diabetes",
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+ "Aspirin prevents platelet aggregation and blood clots",
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+ "Statins lower LDL cholesterol and reduce cardiovascular risk"
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+ ]
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+
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+ # Query
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+ query = "What medication treats high blood sugar?"
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+
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+ # Encode and search
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+ doc_emb = model.encode(docs, convert_to_tensor=True)
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+ query_emb = model.encode(query, convert_to_tensor=True)
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+
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+ hits = util.semantic_search(query_emb, doc_emb, top_k=2)[0]
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+
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+ for hit in hits:
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+ print(f"Score: {hit['score']:.4f} - {docs[hit['corpus_id']]}")
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+ ```
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+
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+ ---
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+
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+ ## πŸ”— Collection Links
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+
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+ **BioForge Collection**: [View all models](https://huggingface.co/collections/pankajrajdeo/bioforge-progressive-biomedical-embeddings)
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+
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+ All Models:
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+ - [Stage 1a: PubMed](https://huggingface.co/pankajrajdeo/bioforge-stage1a-pubmed)
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+ - [Stage 1b: Clinical Trials](https://huggingface.co/pankajrajdeo/bioforge-stage1b-clinical-trials)
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+ - [Stage 1c: UMLS](https://huggingface.co/pankajrajdeo/bioforge-stage1c-umls)
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+ - [BOND: OWL Ontologies](https://huggingface.co/pankajrajdeo/bioforge-bond-owl)
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+ - [Stage 4: Mixed ⭐](https://huggingface.co/pankajrajdeo/bioforge-stage4-mixed)
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+
197
+ ---
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+
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+ ## ⚠️ Limitations
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+
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+ - **Language**: English biomedical text only
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+ - **Domain**: Performance may vary on highly specialized subdomains
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+ - **Medical Use**: Research prototype - not for clinical decisions without validation
204
+ - **Context**: 1024 token limit - chunk longer documents
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+
206
+ ---
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+
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+ ## πŸ“– Citation
209
 
210
  ```bibtex
211
  @software{bioforge2025,
 
218
  }
219
  ```
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221
+ ---
 
 
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223
+ ## πŸ“ž Contact
224
 
225
  - **Author**: Pankaj Rajdeo
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  - **Institution**: Cincinnati Children's Hospital Medical Center
227
  - **Hugging Face**: [@pankajrajdeo](https://huggingface.co/pankajrajdeo)
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+
229
+ ---
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+
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+ ## πŸ… License
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+
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+ MIT License - See [LICENSE](https://huggingface.co/pankajrajdeo/bioforge-stage4-mixed/blob/main/LICENSE)
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+
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+ ---
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+
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+ **Part of the BioForge Progressive Training Collection** | **[View Collection](https://huggingface.co/collections/pankajrajdeo/bioforge-progressive-biomedical-embeddings)**