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Predict drugs for the central gene based on its neighborhood:
Central node: NAT2
One-hop neighbors: [process, Biological Process::GO:0071466], [process, Biological Process::GO:0009410], [process, Biological Process::GO:0006805]
[molecular function, Molecular Function::GO:0004060], [molecular function, Molecular Function::GO:0008080], [molecular function, Molecular Function::GO:0016746], [molecular function, Molecular Function::GO:0016407], [molecular function, Molecular Function::GO:0016747]
Answer:
|
- Isoniazid
- Dapsone
- Sulfamethoxazole
- Clonazepam
- Acetaminophen
- Ezogabine
|
Predict drugs for the central gene based on its neighborhood:
Central node: ADA
One-hop neighbors: [process, Biological Process::GO:0009204], [process, Biological Process::GO:0002314], [process, Biological Process::GO:0002313], [process, Biological Process::GO:0002366], [process, Biological Process::GO:0070255]
[molecular function, Molecular Function::GO:0004000], [molecular function, Molecular Function::GO:0016814], [molecular function, Molecular Function::GO:0019239], [molecular function, Molecular Function::GO:0016810]
[location, Cellular Component::GO:0009897], [location, Cellular Component::GO:0099568], [location, Cellular Component::GO:0000323], [location, Cellular Component::GO:0031983], [location, Cellular Component::GO:0098552]
Answer:
|
- Pentostatin
- Adenosine
- Edetic Acid
- Nelarabine
- Vidarabine
- Theophylline
- Dipyridamole
|
Predict drugs for the central gene based on its neighborhood:
Central node: HDAC6
One-hop neighbors: [process, Biological Process::GO:0043241], [process, Biological Process::GO:0016568], [process, Biological Process::GO:0051129], [process, Biological Process::GO:0030334], [process, Biological Process::GO:2000147]
[molecular function, Molecular Function::GO:0001047], [molecular function, Molecular Function::GO:0032182], [molecular function, Molecular Function::GO:0016811], [molecular function, Molecular Function::GO:0048487], [molecular function, Molecular Function::GO:0070840]
[location, Cellular Component::GO:0099512], [location, Cellular Component::GO:0005768], [location, Cellular Component::GO:0048471], [location, Cellular Component::GO:0016235], [location, Cellular Component::GO:0036477]
Answer:
|
- Vorinostat
|
Predict drugs for the central gene based on its neighborhood:
Central node: SBK3
One-hop neighbors: [process, Biological Process::GO:0006468]
[molecular function, Molecular Function::GO:0004672], [molecular function, Molecular Function::GO:0016772], [molecular function, Molecular Function::GO:0016773], [molecular function, Molecular Function::GO:0016301], [molecular function, Molecular Function::GO:0004674]
Answer:
|
- Crizotinib
|
Predict drugs for the central gene based on its neighborhood:
Central node: SH2B3
One-hop neighbors: [process, Biological Process::GO:0009790], [process, Biological Process::GO:0002520], [process, Biological Process::GO:0048534], [process, Biological Process::GO:0030097], [process, Biological Process::GO:0042060]
[molecular function, Molecular Function::GO:0060090], [molecular function, Molecular Function::GO:0035591]
Answer:
|
- Pazopanib
|
Predict drugs for the central gene based on its neighborhood:
Central node: HCN4
One-hop neighbors: [process, Biological Process::GO:0099536], [process, Biological Process::GO:0055117], [process, Biological Process::GO:1901699], [process, Biological Process::GO:0010243], [process, Biological Process::GO:0008015]
[molecular function, Molecular Function::GO:0022838], [molecular function, Molecular Function::GO:0005272], [molecular function, Molecular Function::GO:0030551], [molecular function, Molecular Function::GO:0022843], [molecular function, Molecular Function::GO:0005222]
[location, Cellular Component::GO:0048471]
Answer:
|
- Dronedarone
|
Predict drugs for the central gene based on its neighborhood:
Central node: CDH5
One-hop neighbors: [process, Biological Process::GO:0071560], [process, Biological Process::GO:0001955], [process, Biological Process::GO:0032878], [process, Biological Process::GO:0045601], [process, Biological Process::GO:0007179]
[molecular function, Molecular Function::GO:0008013], [molecular function, Molecular Function::GO:0019903], [molecular function, Molecular Function::GO:0044325], [molecular function, Molecular Function::GO:0019902], [molecular function, Molecular Function::GO:0005509]
[location, Cellular Component::GO:0098552], [location, Cellular Component::GO:0070161], [location, Cellular Component::GO:0005911], [location, Cellular Component::GO:0070160], [location, Cellular Component::GO:0009897]
Answer:
|
- Lenalidomide
|
Predict drugs for the central gene based on its neighborhood:
Central node: C8orf44-SGK3
One-hop neighbors: [process, Biological Process::GO:0055067], [process, Biological Process::GO:0030003], [process, Biological Process::GO:0032411], [process, Biological Process::GO:0018209], [process, Biological Process::GO:0040012]
[molecular function, Molecular Function::GO:0016772], [molecular function, Molecular Function::GO:0005246], [molecular function, Molecular Function::GO:0017080], [molecular function, Molecular Function::GO:0016773], [molecular function, Molecular Function::GO:0004674]
[location, Cellular Component::GO:0005769], [location, Cellular Component::GO:0005768], [location, Cellular Component::GO:0055037]
Answer:
|
- Sunitinib
|
Predict drugs for the central gene based on its neighborhood:
Central node: FARSB
One-hop neighbors: [process, Biological Process::GO:0043043], [process, Biological Process::GO:0006518], [process, Biological Process::GO:0043038], [process, Biological Process::GO:0006432], [process, Biological Process::GO:0006520]
[molecular function, Molecular Function::GO:0000287], [molecular function, Molecular Function::GO:0016876], [molecular function, Molecular Function::GO:0004826], [molecular function, Molecular Function::GO:0016875], [molecular function, Molecular Function::GO:0004812]
[location, Cellular Component::GO:0009328]
Answer:
|
- L-Phenylalanine
|
Predict drugs for the central gene based on its neighborhood:
Central node: ABCC9
One-hop neighbors: [process, Biological Process::GO:0098542], [process, Biological Process::GO:0006813], [process, Biological Process::GO:0071804], [process, Biological Process::GO:0009607], [process, Biological Process::GO:0061337]
[molecular function, Molecular Function::GO:0022803], [molecular function, Molecular Function::GO:0044325], [molecular function, Molecular Function::GO:0022890], [molecular function, Molecular Function::GO:0015459], [molecular function, Molecular Function::GO:0015075]
[location, Cellular Component::GO:0030016], [location, Cellular Component::GO:0034702], [location, Cellular Component::GO:0008282], [location, Cellular Component::GO:0034703], [location, Cellular Component::GO:1902495]
Answer:
|
- Glyburide
- Minoxidil
- Adenosine triphosphate
|
Predict drugs for the central gene based on its neighborhood:
Central node: PPIF
One-hop neighbors: [process, Biological Process::GO:0090200], [process, Biological Process::GO:0051051], [process, Biological Process::GO:0070301], [process, Biological Process::GO:0000302], [process, Biological Process::GO:0010942]
[molecular function, Molecular Function::GO:0033218], [molecular function, Molecular Function::GO:0016859], [molecular function, Molecular Function::GO:0003755], [molecular function, Molecular Function::GO:0016853], [molecular function, Molecular Function::GO:0042277]
[location, Cellular Component::GO:0005743], [location, Cellular Component::GO:0005740], [location, Cellular Component::GO:0045259], [location, Cellular Component::GO:0005753], [location, Cellular Component::GO:0016469]
Answer:
|
- Cyclosporine
- L-Proline
|
Predict drugs for the central gene based on its neighborhood:
Central node: HIPK3
One-hop neighbors: [process, Biological Process::GO:0043549], [process, Biological Process::GO:0043508], [process, Biological Process::GO:0046328], [process, Biological Process::GO:0006468], [process, Biological Process::GO:0043506]
[molecular function, Molecular Function::GO:0004672], [molecular function, Molecular Function::GO:0016773], [molecular function, Molecular Function::GO:0016301], [molecular function, Molecular Function::GO:0016772], [molecular function, Molecular Function::GO:0004674]
[location, Cellular Component::GO:0016604], [location, Cellular Component::GO:0016605]
Answer:
|
- Sunitinib
- Sorafenib
|
Predict drugs for the central gene based on its neighborhood:
Central node: SLC25A13
One-hop neighbors: [process, Biological Process::GO:0043603], [process, Biological Process::GO:0009126], [process, Biological Process::GO:0022904], [process, Biological Process::GO:0006820], [process, Biological Process::GO:0015800]
[molecular function, Molecular Function::GO:0046943], [molecular function, Molecular Function::GO:0015179], [molecular function, Molecular Function::GO:0015556], [molecular function, Molecular Function::GO:0008509], [molecular function, Molecular Function::GO:0003735]
[location, Cellular Component::GO:0031966], [location, Cellular Component::GO:0005740], [location, Cellular Component::GO:0019866], [location, Cellular Component::GO:0005743]
Answer:
|
- L-Aspartic Acid
|
Predict drugs for the central gene based on its neighborhood:
Central node: SLC25A15
One-hop neighbors: [process, Biological Process::GO:0006812], [process, Biological Process::GO:1902475], [process, Biological Process::GO:0009308], [process, Biological Process::GO:0006839], [process, Biological Process::GO:0003333]
[molecular function, Molecular Function::GO:0015075], [molecular function, Molecular Function::GO:0005342], [molecular function, Molecular Function::GO:0022891], [molecular function, Molecular Function::GO:0046943], [molecular function, Molecular Function::GO:0015179]
[location, Cellular Component::GO:0005743], [location, Cellular Component::GO:0031966], [location, Cellular Component::GO:0005740], [location, Cellular Component::GO:0019866]
Answer:
|
- L-Ornithine
|
Predict drugs for the central gene based on its neighborhood:
Central node: CDK2
One-hop neighbors: [process, Biological Process::GO:0031145], [process, Biological Process::GO:0072431], [process, Biological Process::GO:0072331], [process, Biological Process::GO:0043632], [process, Biological Process::GO:1902400]
[molecular function, Molecular Function::GO:0032403], [molecular function, Molecular Function::GO:0097472], [molecular function, Molecular Function::GO:0004693], [molecular function, Molecular Function::GO:0016301], [molecular function, Molecular Function::GO:0004674]
[location, Cellular Component::GO:0016604], [location, Cellular Component::GO:0005768], [location, Cellular Component::GO:0005667], [location, Cellular Component::GO:0005815], [location, Cellular Component::GO:1902911]
Answer:
|
- Bosutinib
|
Predict drugs for the central gene based on its neighborhood:
Central node: TNK2
One-hop neighbors: [process, Biological Process::GO:0060627], [process, Biological Process::GO:2000369], [process, Biological Process::GO:0018212], [process, Biological Process::GO:0007169], [process, Biological Process::GO:0050731]
[molecular function, Molecular Function::GO:0004713], [molecular function, Molecular Function::GO:0016773], [molecular function, Molecular Function::GO:0016772], [molecular function, Molecular Function::GO:0070851], [molecular function, Molecular Function::GO:0050699]
[location, Cellular Component::GO:0043025], [location, Cellular Component::GO:0030136], [location, Cellular Component::GO:0030135], [location, Cellular Component::GO:0031234], [location, Cellular Component::GO:0036477]
Answer:
|
- Bosutinib
- Crizotinib
- Dasatinib
- Adenosine triphosphate
|
Predict drugs for the central gene based on its neighborhood:
Central node: ADAM10
One-hop neighbors: [process, Biological Process::GO:0032101], [process, Biological Process::GO:2000404], [process, Biological Process::GO:0002688], [process, Biological Process::GO:0032103], [process, Biological Process::GO:0009790]
[molecular function, Molecular Function::GO:0017124], [molecular function, Molecular Function::GO:0032403], [molecular function, Molecular Function::GO:0004175], [molecular function, Molecular Function::GO:0019901], [molecular function, Molecular Function::GO:0070011]
[location, Cellular Component::GO:0048471], [location, Cellular Component::GO:0070161], [location, Cellular Component::GO:0005925], [location, Cellular Component::GO:0009986], [location, Cellular Component::GO:0031984]
Answer:
|
- Marimastat
|
Predict drugs for the central gene based on its neighborhood:
Central node: CDK7
One-hop neighbors: [process, Biological Process::GO:0050434], [process, Biological Process::GO:0006283], [process, Biological Process::GO:0040029], [process, Biological Process::GO:0006352], [process, Biological Process::GO:0070911]
[molecular function, Molecular Function::GO:0003712], [molecular function, Molecular Function::GO:0051427], [molecular function, Molecular Function::GO:0050681], [molecular function, Molecular Function::GO:0016773], [molecular function, Molecular Function::GO:0008094]
[location, Cellular Component::GO:1902554], [location, Cellular Component::GO:1990234], [location, Cellular Component::GO:1902911], [location, Cellular Component::GO:0000428], [location, Cellular Component::GO:0005667]
Answer:
|
- Sorafenib
- Crizotinib
|
Predict drugs for the central gene based on its neighborhood:
Central node: KCNMB2
One-hop neighbors: [process, Biological Process::GO:0006813], [process, Biological Process::GO:0050878], [process, Biological Process::GO:0008015], [process, Biological Process::GO:0003018], [process, Biological Process::GO:0034220]
[molecular function, Molecular Function::GO:0005216], [molecular function, Molecular Function::GO:0016248], [molecular function, Molecular Function::GO:0046873], [molecular function, Molecular Function::GO:0022836], [molecular function, Molecular Function::GO:0022891]
[location, Cellular Component::GO:0034702], [location, Cellular Component::GO:0098797], [location, Cellular Component::GO:1902495], [location, Cellular Component::GO:0034703], [location, Cellular Component::GO:0098796]
Answer:
|
- Miconazole
|
Predict drugs for the central gene based on its neighborhood:
Central node: GLYAT
One-hop neighbors: [process, Biological Process::GO:0035383], [process, Biological Process::GO:0051186], [process, Biological Process::GO:0006637], [process, Biological Process::GO:0032787], [process, Biological Process::GO:0071466]
[molecular function, Molecular Function::GO:0047961], [molecular function, Molecular Function::GO:0016410], [molecular function, Molecular Function::GO:0016746], [molecular function, Molecular Function::GO:0016747]
[location, Cellular Component::GO:0005759]
Answer:
|
- Glycine
|
Predict drugs for the central gene based on its neighborhood:
Central node: LOC102724428
One-hop neighbors:
Answer:
|
- Bosutinib
- Dasatinib
- Dabrafenib
|
Predict drugs for the central gene based on its neighborhood:
Central node: LOC102724560
One-hop neighbors:
Answer:
|
- S-Adenosylmethionine
- L-Cysteine
- L-Serine
|
Predict drugs for the central gene based on its neighborhood:
Central node: LOC400927-CSNK1E
One-hop neighbors: [process, Biological Process::GO:0060828], [process, Biological Process::GO:0009894], [process, Biological Process::GO:0000278], [process, Biological Process::GO:0007623], [process, Biological Process::GO:0032922]
[molecular function, Molecular Function::GO:0016301], [molecular function, Molecular Function::GO:0004674], [molecular function, Molecular Function::GO:0016772], [molecular function, Molecular Function::GO:0004672], [molecular function, Molecular Function::GO:0016773]
[location, Cellular Component::GO:0030529], [location, Cellular Component::GO:1990904]
Answer:
|
- Bosutinib
- Sunitinib
- Gefitinib
|
Predict drugs for the central gene based on its neighborhood:
Central node: MAEA
One-hop neighbors: [process, Biological Process::GO:0030218], [process, Biological Process::GO:0061515], [process, Biological Process::GO:0002262], [process, Biological Process::GO:0048872], [process, Biological Process::GO:0033033]
[molecular function, Molecular Function::GO:0003779], [molecular function, Molecular Function::GO:0008092]
[location, Cellular Component::GO:0070938], [location, Cellular Component::GO:0099568], [location, Cellular Component::GO:0005938], [location, Cellular Component::GO:0032153], [location, Cellular Component::GO:0034399]
Answer:
|
- WF10
|
Predict drugs for the central gene based on its neighborhood:
Central node: AKR1A1
One-hop neighbors: [process, Biological Process::GO:0046394], [process, Biological Process::GO:0046365], [process, Biological Process::GO:0019853], [process, Biological Process::GO:0006767], [process, Biological Process::GO:0006081]
[molecular function, Molecular Function::GO:0004033], [molecular function, Molecular Function::GO:0009055], [molecular function, Molecular Function::GO:0016491], [molecular function, Molecular Function::GO:0016616], [molecular function, Molecular Function::GO:0004032]
[location, Cellular Component::GO:0016324], [location, Cellular Component::GO:0098590], [location, Cellular Component::GO:0045177]
Answer:
|
- Doxorubicin
|
Predict drugs for the central gene based on its neighborhood:
Central node: WARS2
One-hop neighbors: [process, Biological Process::GO:0034660], [process, Biological Process::GO:0006520], [process, Biological Process::GO:0043038], [process, Biological Process::GO:0072358], [process, Biological Process::GO:0048514]
[molecular function, Molecular Function::GO:0016874], [molecular function, Molecular Function::GO:0004830], [molecular function, Molecular Function::GO:0016875], [molecular function, Molecular Function::GO:0016876], [molecular function, Molecular Function::GO:0004812]
[location, Cellular Component::GO:0005759]
Answer:
|
- L-Tryptophan
|
Predict drugs for the central gene based on its neighborhood:
Central node: CDO1
One-hop neighbors: [process, Biological Process::GO:0046394], [process, Biological Process::GO:0006954], [process, Biological Process::GO:0051384], [process, Biological Process::GO:0050878], [process, Biological Process::GO:0097305]
[molecular function, Molecular Function::GO:0051213], [molecular function, Molecular Function::GO:0005506], [molecular function, Molecular Function::GO:0016702], [molecular function, Molecular Function::GO:0016701], [molecular function, Molecular Function::GO:0008198]
Answer:
|
- L-Cysteine
|
Predict drugs for the central gene based on its neighborhood:
Central node: TUBB3
One-hop neighbors: [process, Biological Process::GO:0007411], [process, Biological Process::GO:0007409], [process, Biological Process::GO:0097485], [process, Biological Process::GO:0048812], [process, Biological Process::GO:0006457]
[molecular function, Molecular Function::GO:0016462], [molecular function, Molecular Function::GO:0016817], [molecular function, Molecular Function::GO:0005525], [molecular function, Molecular Function::GO:0017111], [molecular function, Molecular Function::GO:0003924]
[location, Cellular Component::GO:0036477], [location, Cellular Component::GO:0099513], [location, Cellular Component::GO:0005874], [location, Cellular Component::GO:0043025], [location, Cellular Component::GO:0043005]
Answer:
|
- Vinblastine
- Vincristine
- Cabazitaxel
- Ixabepilone
- Docetaxel
- Eribulin
- Paclitaxel
- Vinorelbine
|
Predict drugs for the central gene based on its neighborhood:
Central node: TUBB4A
One-hop neighbors: [process, Biological Process::GO:0044772], [process, Biological Process::GO:0007017], [process, Biological Process::GO:0051084], [process, Biological Process::GO:0006458], [process, Biological Process::GO:0044839]
[molecular function, Molecular Function::GO:0005200], [molecular function, Molecular Function::GO:0017111], [molecular function, Molecular Function::GO:0016817], [molecular function, Molecular Function::GO:0032561], [molecular function, Molecular Function::GO:0005198]
[location, Cellular Component::GO:0033269], [location, Cellular Component::GO:0036477], [location, Cellular Component::GO:0043005], [location, Cellular Component::GO:0099513], [location, Cellular Component::GO:0005874]
Answer:
|
- Vinblastine
- Docetaxel
- Eribulin
- Vinorelbine
- Vincristine
- Ixabepilone
- Cabazitaxel
- Paclitaxel
|
Predict drugs for the central gene based on its neighborhood:
Central node: TUBB4B
One-hop neighbors: [process, Biological Process::GO:0001909], [process, Biological Process::GO:0044770], [process, Biological Process::GO:0000278], [process, Biological Process::GO:0007017], [process, Biological Process::GO:0006457]
[molecular function, Molecular Function::GO:0005200], [molecular function, Molecular Function::GO:0051082], [molecular function, Molecular Function::GO:0016817], [molecular function, Molecular Function::GO:0003725], [molecular function, Molecular Function::GO:0042287]
[location, Cellular Component::GO:0099513], [location, Cellular Component::GO:0043209], [location, Cellular Component::GO:0099512], [location, Cellular Component::GO:0005874]
Answer:
|
- Eribulin
- Docetaxel
- Albendazole
- Vinorelbine
- Ixabepilone
- Paclitaxel
- Vincristine
- Mebendazole
- Vinblastine
- Cabazitaxel
|
Predict drugs for the central gene based on its neighborhood:
Central node: CEPT1
One-hop neighbors: [process, Biological Process::GO:1901615], [process, Biological Process::GO:0090407], [process, Biological Process::GO:0046486], [process, Biological Process::GO:0045017], [process, Biological Process::GO:0006646]
[molecular function, Molecular Function::GO:0004307], [molecular function, Molecular Function::GO:0017169], [molecular function, Molecular Function::GO:0016780], [molecular function, Molecular Function::GO:0016772], [molecular function, Molecular Function::GO:0004142]
[location, Cellular Component::GO:0005789], [location, Cellular Component::GO:0031965], [location, Cellular Component::GO:0042175], [location, Cellular Component::GO:0005635]
Answer:
|
- Choline
|
Predict drugs for the central gene based on its neighborhood:
Central node: ATP8A1
One-hop neighbors: [process, Biological Process::GO:0015711], [process, Biological Process::GO:0044070], [process, Biological Process::GO:0051050], [process, Biological Process::GO:0043269], [process, Biological Process::GO:0098655]
[molecular function, Molecular Function::GO:0004012], [molecular function, Molecular Function::GO:0022804], [molecular function, Molecular Function::GO:0019829], [molecular function, Molecular Function::GO:0016817], [molecular function, Molecular Function::GO:0016820]
[location, Cellular Component::GO:0012506], [location, Cellular Component::GO:0099503], [location, Cellular Component::GO:0005802], [location, Cellular Component::GO:0030659], [location, Cellular Component::GO:0030667]
Answer:
|
- Phosphatidylserine
|
Predict drugs for the central gene based on its neighborhood:
Central node: MERTK
One-hop neighbors: [process, Biological Process::GO:0043069], [process, Biological Process::GO:0048806], [process, Biological Process::GO:0003006], [process, Biological Process::GO:0044703], [process, Biological Process::GO:0000904]
[molecular function, Molecular Function::GO:0004672], [molecular function, Molecular Function::GO:0004713], [molecular function, Molecular Function::GO:0004714], [molecular function, Molecular Function::GO:0016772], [molecular function, Molecular Function::GO:0016773]
[location, Cellular Component::GO:0072372], [location, Cellular Component::GO:0005929], [location, Cellular Component::GO:0001750], [location, Cellular Component::GO:0031513]
Answer:
|
- Bosutinib
- Sunitinib
- Crizotinib
|
Predict drugs for the central gene based on its neighborhood:
Central node: PPIH
One-hop neighbors: [process, Biological Process::GO:0018208], [process, Biological Process::GO:0045069], [process, Biological Process::GO:1903902], [process, Biological Process::GO:0043903], [process, Biological Process::GO:0006396]
[molecular function, Molecular Function::GO:0016859], [molecular function, Molecular Function::GO:0033218], [molecular function, Molecular Function::GO:0016018], [molecular function, Molecular Function::GO:0042277], [molecular function, Molecular Function::GO:0008144]
[location, Cellular Component::GO:0097525], [location, Cellular Component::GO:0030532], [location, Cellular Component::GO:0016607], [location, Cellular Component::GO:1990904], [location, Cellular Component::GO:0097526]
Answer:
|
- L-Proline
|
Predict drugs for the central gene based on its neighborhood:
Central node: STK25
One-hop neighbors: [process, Biological Process::GO:0070304], [process, Biological Process::GO:0001934], [process, Biological Process::GO:1901701], [process, Biological Process::GO:0034599], [process, Biological Process::GO:0006468]
[molecular function, Molecular Function::GO:0042803], [molecular function, Molecular Function::GO:0016772], [molecular function, Molecular Function::GO:0004672], [molecular function, Molecular Function::GO:0016773], [molecular function, Molecular Function::GO:0004674]
[location, Cellular Component::GO:0000139]
Answer:
|
- Bosutinib
|
Predict drugs for the central gene based on its neighborhood:
Central node: P3H3
One-hop neighbors: [process, Biological Process::GO:0019511], [process, Biological Process::GO:0018126], [process, Biological Process::GO:0008285], [process, Biological Process::GO:0018208], [process, Biological Process::GO:0043062]
[molecular function, Molecular Function::GO:0016705], [molecular function, Molecular Function::GO:0030246], [molecular function, Molecular Function::GO:0031406], [molecular function, Molecular Function::GO:0031543], [molecular function, Molecular Function::GO:0031544]
[location, Cellular Component::GO:0005788]
Answer:
|
- Vitamin C
- L-Proline
- Succinic acid
|
Predict drugs for the central gene based on its neighborhood:
Central node: SPTLC1
One-hop neighbors: [process, Biological Process::GO:0030148], [process, Biological Process::GO:0032101], [process, Biological Process::GO:0010508], [process, Biological Process::GO:0006066], [process, Biological Process::GO:0043604]
[molecular function, Molecular Function::GO:0030170], [molecular function, Molecular Function::GO:0048037], [molecular function, Molecular Function::GO:0016454], [molecular function, Molecular Function::GO:0016746], [molecular function, Molecular Function::GO:0004758]
[location, Cellular Component::GO:0035339], [location, Cellular Component::GO:1990234], [location, Cellular Component::GO:0031211], [location, Cellular Component::GO:0098796], [location, Cellular Component::GO:0002178]
Answer:
|
- L-Serine
|
Predict drugs for the central gene based on its neighborhood:
Central node: SLC19A2
One-hop neighbors: [process, Biological Process::GO:0071934], [process, Biological Process::GO:0051180], [process, Biological Process::GO:0006835], [process, Biological Process::GO:0015711], [process, Biological Process::GO:0045117]
[molecular function, Molecular Function::GO:1901474], [molecular function, Molecular Function::GO:0015563], [molecular function, Molecular Function::GO:0015403], [molecular function, Molecular Function::GO:0051184], [molecular function, Molecular Function::GO:0045118]
Answer:
|
- Thiamine
|
Predict drugs for the central gene based on its neighborhood:
Central node: PAICS
One-hop neighbors: [process, Biological Process::GO:0009161], [process, Biological Process::GO:0046148], [process, Biological Process::GO:1901293], [process, Biological Process::GO:0009127], [process, Biological Process::GO:0055086]
[molecular function, Molecular Function::GO:0016881], [molecular function, Molecular Function::GO:0016831], [molecular function, Molecular Function::GO:0016829], [molecular function, Molecular Function::GO:0016879], [molecular function, Molecular Function::GO:0016830]
Answer:
|
- L-Aspartic Acid
|
Predict drugs for the central gene based on its neighborhood:
Central node: FARS2
One-hop neighbors: [process, Biological Process::GO:0006418], [process, Biological Process::GO:0019752], [process, Biological Process::GO:0006412], [process, Biological Process::GO:0043603], [process, Biological Process::GO:0034660]
[molecular function, Molecular Function::GO:0000049], [molecular function, Molecular Function::GO:0000287], [molecular function, Molecular Function::GO:0016875], [molecular function, Molecular Function::GO:0016874], [molecular function, Molecular Function::GO:0004826]
[location, Cellular Component::GO:0005759]
Answer:
|
- L-Phenylalanine
|
Predict drugs for the central gene based on its neighborhood:
Central node: EBP
One-hop neighbors: [process, Biological Process::GO:0006694], [process, Biological Process::GO:1901617], [process, Biological Process::GO:1901615], [process, Biological Process::GO:0033489], [process, Biological Process::GO:0002520]
[molecular function, Molecular Function::GO:0016860], [molecular function, Molecular Function::GO:0016853], [molecular function, Molecular Function::GO:0016863], [molecular function, Molecular Function::GO:0047750], [molecular function, Molecular Function::GO:0090484]
[location, Cellular Component::GO:0042175], [location, Cellular Component::GO:0005789]
Answer:
|
- Haloperidol
- Tamoxifen
- Clomifene
- Raloxifene
- Pentazocine
- Amiodarone
- Trifluoperazine
- Ifenprodil
|
Predict drugs for the central gene based on its neighborhood:
Central node: SLC12A7
One-hop neighbors: [process, Biological Process::GO:0019725], [process, Biological Process::GO:0099537], [process, Biological Process::GO:0007267], [process, Biological Process::GO:0098660], [process, Biological Process::GO:0015672]
[molecular function, Molecular Function::GO:0008324], [molecular function, Molecular Function::GO:0015291], [molecular function, Molecular Function::GO:0022890], [molecular function, Molecular Function::GO:0022857], [molecular function, Molecular Function::GO:0046873]
Answer:
|
- Potassium Chloride
|
Predict drugs for the central gene based on its neighborhood:
Central node: PLK4
One-hop neighbors: [process, Biological Process::GO:0001890], [process, Biological Process::GO:0001892], [process, Biological Process::GO:0006468], [process, Biological Process::GO:0010824], [process, Biological Process::GO:0051493]
[molecular function, Molecular Function::GO:0016301], [molecular function, Molecular Function::GO:0004674], [molecular function, Molecular Function::GO:0016772], [molecular function, Molecular Function::GO:0004672], [molecular function, Molecular Function::GO:0016773]
[location, Cellular Component::GO:0005814], [location, Cellular Component::GO:0009986], [location, Cellular Component::GO:0032154], [location, Cellular Component::GO:0001741], [location, Cellular Component::GO:0005730]
Answer:
|
- Vandetanib
- Ruxolitinib
- Sunitinib
- Crizotinib
- Pazopanib
|
Predict drugs for the central gene based on its neighborhood:
Central node: MAP3K2
One-hop neighbors: [process, Biological Process::GO:0023014], [process, Biological Process::GO:0051347], [process, Biological Process::GO:0045859], [process, Biological Process::GO:0043406], [process, Biological Process::GO:0007257]
[molecular function, Molecular Function::GO:0005057], [molecular function, Molecular Function::GO:0004709], [molecular function, Molecular Function::GO:0016773], [molecular function, Molecular Function::GO:0004672], [molecular function, Molecular Function::GO:0019901]
Answer:
|
- Pazopanib
- Sunitinib
- Ruxolitinib
- Crizotinib
- Bosutinib
- Dasatinib
|
Predict drugs for the central gene based on its neighborhood:
Central node: PLK2
One-hop neighbors: [process, Biological Process::GO:1901800], [process, Biological Process::GO:0050768], [process, Biological Process::GO:0000075], [process, Biological Process::GO:2000171], [process, Biological Process::GO:0045665]
[molecular function, Molecular Function::GO:0004672], [molecular function, Molecular Function::GO:0032403], [molecular function, Molecular Function::GO:0004674], [molecular function, Molecular Function::GO:0016301], [molecular function, Molecular Function::GO:0016773]
[location, Cellular Component::GO:0043005], [location, Cellular Component::GO:0005813], [location, Cellular Component::GO:0030425], [location, Cellular Component::GO:0000785], [location, Cellular Component::GO:0005694]
Answer:
|
- Bosutinib
|
Predict drugs for the central gene based on its neighborhood:
Central node: MTHFD2
One-hop neighbors: [process, Biological Process::GO:0009108], [process, Biological Process::GO:0006760], [process, Biological Process::GO:0042558], [process, Biological Process::GO:0009396], [process, Biological Process::GO:0055114]
[molecular function, Molecular Function::GO:0004488], [molecular function, Molecular Function::GO:0016814], [molecular function, Molecular Function::GO:0016491], [molecular function, Molecular Function::GO:0042301], [molecular function, Molecular Function::GO:0016646]
Answer:
|
- Tetrahydrofolic acid
|
Predict drugs for the central gene based on its neighborhood:
Central node: CFTR
One-hop neighbors: [process, Biological Process::GO:0010876], [process, Biological Process::GO:0007283], [process, Biological Process::GO:0007281], [process, Biological Process::GO:0019725], [process, Biological Process::GO:2001225]
[molecular function, Molecular Function::GO:0016248], [molecular function, Molecular Function::GO:0008514], [molecular function, Molecular Function::GO:0022804], [molecular function, Molecular Function::GO:0015075], [molecular function, Molecular Function::GO:0015103]
[location, Cellular Component::GO:0098852], [location, Cellular Component::GO:0031901], [location, Cellular Component::GO:0098796], [location, Cellular Component::GO:0045177], [location, Cellular Component::GO:0005774]
Answer:
|
- Bumetanide
- Ivacaftor
- Glyburide
- Ibuprofen
|
Predict drugs for the central gene based on its neighborhood:
Central node: CYSLTR1
One-hop neighbors: [process, Biological Process::GO:0003013], [process, Biological Process::GO:0055065], [process, Biological Process::GO:0030001], [process, Biological Process::GO:0072507], [process, Biological Process::GO:0019725]
[molecular function, Molecular Function::GO:0004930], [molecular function, Molecular Function::GO:0008528], [molecular function, Molecular Function::GO:0001653], [molecular function, Molecular Function::GO:0004974], [molecular function, Molecular Function::GO:0001631]
Answer:
|
- Pranlukast
- Montelukast
- Cinalukast
- Nedocromil
- Zafirlukast
|
Predict drugs for the central gene based on its neighborhood:
Central node: ALDH1L1
One-hop neighbors: [process, Biological Process::GO:0044282], [process, Biological Process::GO:1901361], [process, Biological Process::GO:1901565], [process, Biological Process::GO:0006732], [process, Biological Process::GO:0042219]
[molecular function, Molecular Function::GO:0016491], [molecular function, Molecular Function::GO:0016620], [molecular function, Molecular Function::GO:0016741], [molecular function, Molecular Function::GO:0016742], [molecular function, Molecular Function::GO:0016646]
Answer:
|
- Tetrahydrofolic acid
|
Predict drugs for the central gene based on its neighborhood:
Central node: FTCD
One-hop neighbors: [process, Biological Process::GO:0006547], [process, Biological Process::GO:0032787], [process, Biological Process::GO:0043648], [process, Biological Process::GO:0019556], [process, Biological Process::GO:1901565]
[molecular function, Molecular Function::GO:0043177], [molecular function, Molecular Function::GO:0019239], [molecular function, Molecular Function::GO:0016741], [molecular function, Molecular Function::GO:0016742], [molecular function, Molecular Function::GO:0008017]
[location, Cellular Component::GO:0000139], [location, Cellular Component::GO:0005793], [location, Cellular Component::GO:0005814], [location, Cellular Component::GO:0005815], [location, Cellular Component::GO:0005813]
Answer:
|
- Tetrahydrofolic acid
|
Predict drugs for the central gene based on its neighborhood:
Central node: PDE10A
One-hop neighbors: [process, Biological Process::GO:0009150], [process, Biological Process::GO:0034655], [process, Biological Process::GO:0046434], [process, Biological Process::GO:0019637], [process, Biological Process::GO:0009259]
[molecular function, Molecular Function::GO:0032561], [molecular function, Molecular Function::GO:0016788], [molecular function, Molecular Function::GO:0030551], [molecular function, Molecular Function::GO:0030552], [molecular function, Molecular Function::GO:0047555]
[location, Cellular Component::GO:0043025], [location, Cellular Component::GO:0043204], [location, Cellular Component::GO:0044297], [location, Cellular Component::GO:0036477]
Answer:
|
- Tofisopam
- Dipyridamole
- Papaverine
- Vardenafil
|
Predict drugs for the central gene based on its neighborhood:
Central node: PGRMC1
One-hop neighbors: [molecular function, Molecular Function::GO:0008289], [molecular function, Molecular Function::GO:0005496], [molecular function, Molecular Function::GO:0046906], [molecular function, Molecular Function::GO:0020037]
[location, Cellular Component::GO:0042175], [location, Cellular Component::GO:0005789], [location, Cellular Component::GO:0005730]
Answer:
|
- Dextromethorphan
|
Predict drugs for the central gene based on its neighborhood:
Central node: MMP24
One-hop neighbors: [process, Biological Process::GO:0009581], [process, Biological Process::GO:0050951], [process, Biological Process::GO:0098727], [process, Biological Process::GO:0050906], [process, Biological Process::GO:0098609]
[molecular function, Molecular Function::GO:0005509], [molecular function, Molecular Function::GO:0008047], [molecular function, Molecular Function::GO:0008233], [molecular function, Molecular Function::GO:0045296], [molecular function, Molecular Function::GO:0050839]
[location, Cellular Component::GO:0031012], [location, Cellular Component::GO:0005802], [location, Cellular Component::GO:0032588], [location, Cellular Component::GO:0098791], [location, Cellular Component::GO:0000139]
Answer:
|
- Marimastat
|
Predict drugs for the central gene based on its neighborhood:
Central node: DHRS4
One-hop neighbors: [process, Biological Process::GO:0008202], [process, Biological Process::GO:0051262], [process, Biological Process::GO:0042180], [process, Biological Process::GO:1901615], [process, Biological Process::GO:0006066]
[molecular function, Molecular Function::GO:0016616], [molecular function, Molecular Function::GO:0016614], [molecular function, Molecular Function::GO:0016651], [molecular function, Molecular Function::GO:0000253], [molecular function, Molecular Function::GO:0004090]
[location, Cellular Component::GO:0042175], [location, Cellular Component::GO:0005778], [location, Cellular Component::GO:0005777], [location, Cellular Component::GO:0031965], [location, Cellular Component::GO:0005789]
Answer:
|
- Vitamin A
|
Predict drugs for the central gene based on its neighborhood:
Central node: RALBP1
One-hop neighbors: [process, Biological Process::GO:0043087], [process, Biological Process::GO:0006935], [process, Biological Process::GO:0043547], [process, Biological Process::GO:0007264], [process, Biological Process::GO:0006897]
[molecular function, Molecular Function::GO:0017016], [molecular function, Molecular Function::GO:0030695], [molecular function, Molecular Function::GO:0060589], [molecular function, Molecular Function::GO:0008047], [molecular function, Molecular Function::GO:0016462]
Answer:
|
- Vincristine
- Doxorubicin
- Carbamazepine
- Sorafenib
|
Predict drugs for the central gene based on its neighborhood:
Central node: AFG3L2
One-hop neighbors: [process, Biological Process::GO:0061024], [process, Biological Process::GO:0070585], [process, Biological Process::GO:0044743], [process, Biological Process::GO:0065002], [process, Biological Process::GO:0033365]
[molecular function, Molecular Function::GO:0051082], [molecular function, Molecular Function::GO:0004222], [molecular function, Molecular Function::GO:0070011], [molecular function, Molecular Function::GO:0016887], [molecular function, Molecular Function::GO:0008237]
[location, Cellular Component::GO:0005740], [location, Cellular Component::GO:0005743], [location, Cellular Component::GO:0019866], [location, Cellular Component::GO:0031966]
Answer:
|
- Adenosine triphosphate
|
Predict drugs for the central gene based on its neighborhood:
Central node: METAP2
One-hop neighbors: [process, Biological Process::GO:0071478], [process, Biological Process::GO:0007603], [process, Biological Process::GO:0071482], [process, Biological Process::GO:0009583], [process, Biological Process::GO:0016485]
[molecular function, Molecular Function::GO:0070011], [molecular function, Molecular Function::GO:0004177], [molecular function, Molecular Function::GO:0008235], [molecular function, Molecular Function::GO:0070006], [molecular function, Molecular Function::GO:0008237]
Answer:
|
- Nitroxoline
- L-Methionine
|
Predict drugs for the central gene based on its neighborhood:
Central node: SDS
One-hop neighbors: [process, Biological Process::GO:0044723], [process, Biological Process::GO:0006094], [process, Biological Process::GO:0016054], [process, Biological Process::GO:0046395], [process, Biological Process::GO:0044712]
[molecular function, Molecular Function::GO:0048037], [molecular function, Molecular Function::GO:0030170], [molecular function, Molecular Function::GO:0016841], [molecular function, Molecular Function::GO:0016829], [molecular function, Molecular Function::GO:0016840]
Answer:
|
- L-Serine
|
Predict drugs for the central gene based on its neighborhood:
Central node: TLK2
One-hop neighbors: [process, Biological Process::GO:0042177], [process, Biological Process::GO:0071214], [process, Biological Process::GO:0007059], [process, Biological Process::GO:0010332], [process, Biological Process::GO:0009314]
[molecular function, Molecular Function::GO:0016773], [molecular function, Molecular Function::GO:0004674], [molecular function, Molecular Function::GO:0016772], [molecular function, Molecular Function::GO:0016301], [molecular function, Molecular Function::GO:0004672]
[location, Cellular Component::GO:0005882], [location, Cellular Component::GO:0048471], [location, Cellular Component::GO:0045111], [location, Cellular Component::GO:0099512], [location, Cellular Component::GO:0099513]
Answer:
|
- Sunitinib
|
Predict drugs for the central gene based on its neighborhood:
Central node: LIAS
One-hop neighbors: [process, Biological Process::GO:0035239], [process, Biological Process::GO:0044272], [process, Biological Process::GO:0032787], [process, Biological Process::GO:0006081], [process, Biological Process::GO:0051188]
[molecular function, Molecular Function::GO:0016874], [molecular function, Molecular Function::GO:0051536], [molecular function, Molecular Function::GO:0016782], [molecular function, Molecular Function::GO:0051539], [molecular function, Molecular Function::GO:0016879]
[location, Cellular Component::GO:0005759]
Answer:
|
- Lipoic Acid
|
Predict drugs for the central gene based on its neighborhood:
Central node: CHAT
One-hop neighbors: [process, Biological Process::GO:0007548], [process, Biological Process::GO:0042493], [process, Biological Process::GO:0048609], [process, Biological Process::GO:0048589], [process, Biological Process::GO:0044708]
[molecular function, Molecular Function::GO:0016407], [molecular function, Molecular Function::GO:0033265], [molecular function, Molecular Function::GO:0070405], [molecular function, Molecular Function::GO:0050997], [molecular function, Molecular Function::GO:0016413]
[location, Cellular Component::GO:0043005]
Answer:
|
- Choline
- Nicotine
|
Predict drugs for the central gene based on its neighborhood:
Central node: CHD1
One-hop neighbors: [process, Biological Process::GO:0051817], [process, Biological Process::GO:0044419], [process, Biological Process::GO:0051851], [process, Biological Process::GO:0043923], [process, Biological Process::GO:0048524]
[molecular function, Molecular Function::GO:0042393], [molecular function, Molecular Function::GO:0004003], [molecular function, Molecular Function::GO:0035064], [molecular function, Molecular Function::GO:0003678], [molecular function, Molecular Function::GO:0042623]
Answer:
|
- Epirubicin
|
Predict drugs for the central gene based on its neighborhood:
Central node: SLC7A9
One-hop neighbors: [process, Biological Process::GO:0003333], [process, Biological Process::GO:0007596], [process, Biological Process::GO:0098656], [process, Biological Process::GO:0000101], [process, Biological Process::GO:0050900]
[molecular function, Molecular Function::GO:0015184], [molecular function, Molecular Function::GO:0022891], [molecular function, Molecular Function::GO:0015297], [molecular function, Molecular Function::GO:0005342], [molecular function, Molecular Function::GO:0015075]
[location, Cellular Component::GO:0098590], [location, Cellular Component::GO:0031253], [location, Cellular Component::GO:0045177], [location, Cellular Component::GO:0098862], [location, Cellular Component::GO:0031526]
Answer:
|
- L-Cystine
|
Predict drugs for the central gene based on its neighborhood:
Central node: PSIP1
One-hop neighbors: [process, Biological Process::GO:0016032], [process, Biological Process::GO:0022613], [process, Biological Process::GO:0000377], [process, Biological Process::GO:0000375], [process, Biological Process::GO:0071826]
[molecular function, Molecular Function::GO:0003682], [molecular function, Molecular Function::GO:0001104], [molecular function, Molecular Function::GO:0001105], [molecular function, Molecular Function::GO:0000988], [molecular function, Molecular Function::GO:0008134]
[location, Cellular Component::GO:0000785], [location, Cellular Component::GO:0000228], [location, Cellular Component::GO:0005720], [location, Cellular Component::GO:0035327], [location, Cellular Component::GO:0005694]
Answer:
|
- L-DOPA
|
Predict drugs for the central gene based on its neighborhood:
Central node: MAP4K5
One-hop neighbors: [process, Biological Process::GO:0043406], [process, Biological Process::GO:0043506], [process, Biological Process::GO:0045859], [process, Biological Process::GO:0071900], [process, Biological Process::GO:1902533]
[molecular function, Molecular Function::GO:0004672], [molecular function, Molecular Function::GO:0004702], [molecular function, Molecular Function::GO:0016772], [molecular function, Molecular Function::GO:0005057], [molecular function, Molecular Function::GO:0008349]
Answer:
|
- Bosutinib
- Dasatinib
- Vandetanib
- Sunitinib
- Crizotinib
|
Predict drugs for the central gene based on its neighborhood:
Central node: MAP4K1
One-hop neighbors: [process, Biological Process::GO:0071902], [process, Biological Process::GO:0043406], [process, Biological Process::GO:0008283], [process, Biological Process::GO:0070302], [process, Biological Process::GO:0000185]
[molecular function, Molecular Function::GO:0005057], [molecular function, Molecular Function::GO:0004672], [molecular function, Molecular Function::GO:0016301], [molecular function, Molecular Function::GO:0004702], [molecular function, Molecular Function::GO:0016772]
Answer:
|
- Crizotinib
- Bosutinib
- Nilotinib
- Sunitinib
|
Predict drugs for the central gene based on its neighborhood:
Central node: NISCH
One-hop neighbors: [process, Biological Process::GO:0008015], [process, Biological Process::GO:0046903], [process, Biological Process::GO:0003013], [process, Biological Process::GO:2000146], [process, Biological Process::GO:0030029]
[molecular function, Molecular Function::GO:0005543], [molecular function, Molecular Function::GO:0032403], [molecular function, Molecular Function::GO:0005178], [molecular function, Molecular Function::GO:0008289], [molecular function, Molecular Function::GO:0050839]
[location, Cellular Component::GO:0005769], [location, Cellular Component::GO:0005768], [location, Cellular Component::GO:0055037]
Answer:
|
- Oxymetazoline
- Tizanidine
- Naphazoline
- Phentolamine
- Clonidine
- Guanfacine
- Guanabenz
|
Predict drugs for the central gene based on its neighborhood:
Central node: CHKA
One-hop neighbors: [process, Biological Process::GO:0006657], [process, Biological Process::GO:0008610], [process, Biological Process::GO:0006066], [process, Biological Process::GO:0010876], [process, Biological Process::GO:0042439]
[molecular function, Molecular Function::GO:0016301], [molecular function, Molecular Function::GO:0016773], [molecular function, Molecular Function::GO:0016772], [molecular function, Molecular Function::GO:0070405], [molecular function, Molecular Function::GO:0050997]
Answer:
|
- Choline
|
Predict drugs for the central gene based on its neighborhood:
Central node: CHKB
One-hop neighbors: [process, Biological Process::GO:0045017], [process, Biological Process::GO:0046165], [process, Biological Process::GO:0046337], [process, Biological Process::GO:0019637], [process, Biological Process::GO:0006576]
[molecular function, Molecular Function::GO:0016772], [molecular function, Molecular Function::GO:0004103], [molecular function, Molecular Function::GO:0016301], [molecular function, Molecular Function::GO:0016773], [molecular function, Molecular Function::GO:0004305]
Answer:
|
- Choline
|
Predict drugs for the central gene based on its neighborhood:
Central node: CHEK2
One-hop neighbors: [process, Biological Process::GO:0051053], [process, Biological Process::GO:0072422], [process, Biological Process::GO:0090307], [process, Biological Process::GO:0044774], [process, Biological Process::GO:1902403]
[molecular function, Molecular Function::GO:0019900], [molecular function, Molecular Function::GO:0042803], [molecular function, Molecular Function::GO:0004674], [molecular function, Molecular Function::GO:0044389], [molecular function, Molecular Function::GO:0031625]
[location, Cellular Component::GO:0005694], [location, Cellular Component::GO:0016604], [location, Cellular Component::GO:0016605], [location, Cellular Component::GO:0000781], [location, Cellular Component::GO:0098687]
Answer:
|
- Bosutinib
- Gefitinib
- Sunitinib
|
Predict drugs for the central gene based on its neighborhood:
Central node: PROSC
One-hop neighbors: [molecular function, Molecular Function::GO:0048037], [molecular function, Molecular Function::GO:0030170]
Answer:
|
- L-Proline
|
Predict drugs for the central gene based on its neighborhood:
Central node: EGLN2
One-hop neighbors: [process, Biological Process::GO:0043523], [process, Biological Process::GO:0045454], [process, Biological Process::GO:0018208], [process, Biological Process::GO:0018401], [process, Biological Process::GO:0045732]
[molecular function, Molecular Function::GO:0008198], [molecular function, Molecular Function::GO:0043177], [molecular function, Molecular Function::GO:0051213], [molecular function, Molecular Function::GO:0016705], [molecular function, Molecular Function::GO:0031545]
Answer:
|
- Vitamin C
|
Predict drugs for the central gene based on its neighborhood:
Central node: EGLN3
One-hop neighbors: [process, Biological Process::GO:0061418], [process, Biological Process::GO:0071456], [process, Biological Process::GO:0032787], [process, Biological Process::GO:0010942], [process, Biological Process::GO:1901605]
[molecular function, Molecular Function::GO:0051213], [molecular function, Molecular Function::GO:0031418], [molecular function, Molecular Function::GO:0016705], [molecular function, Molecular Function::GO:0005506], [molecular function, Molecular Function::GO:0016491]
Answer:
|
- Vitamin C
|
Predict drugs for the central gene based on its neighborhood:
Central node: PADI2
One-hop neighbors: [process, Biological Process::GO:0008652], [process, Biological Process::GO:1901624], [process, Biological Process::GO:0006338], [process, Biological Process::GO:0040029], [process, Biological Process::GO:1901605]
[molecular function, Molecular Function::GO:0051427], [molecular function, Molecular Function::GO:0016813], [molecular function, Molecular Function::GO:0035257], [molecular function, Molecular Function::GO:0030331], [molecular function, Molecular Function::GO:0035258]
[location, Cellular Component::GO:0005694], [location, Cellular Component::GO:0035327], [location, Cellular Component::GO:0000785]
Answer:
|
- L-Citrulline
|
Predict drugs for the central gene based on its neighborhood:
Central node: SAT2
One-hop neighbors: [process, Biological Process::GO:0006598], [process, Biological Process::GO:0042402], [process, Biological Process::GO:0006576], [process, Biological Process::GO:0044106], [process, Biological Process::GO:0009310]
[molecular function, Molecular Function::GO:0016410], [molecular function, Molecular Function::GO:0016747], [molecular function, Molecular Function::GO:0016746], [molecular function, Molecular Function::GO:0008080], [molecular function, Molecular Function::GO:0016407]
Answer:
|
- Spermine
|
Predict drugs for the central gene based on its neighborhood:
Central node: PTGDR2
One-hop neighbors: [process, Biological Process::GO:2000241], [process, Biological Process::GO:0007187], [process, Biological Process::GO:0007218], [process, Biological Process::GO:0007268], [process, Biological Process::GO:0099537]
[molecular function, Molecular Function::GO:0042277], [molecular function, Molecular Function::GO:0004930], [molecular function, Molecular Function::GO:0004955], [molecular function, Molecular Function::GO:0004958], [molecular function, Molecular Function::GO:0042923]
[location, Cellular Component::GO:0043005]
Answer:
|
- Sulindac
- Indomethacin
|
Predict drugs for the central gene based on its neighborhood:
Central node: SLC6A14
One-hop neighbors: [process, Biological Process::GO:0006865], [process, Biological Process::GO:0009636], [process, Biological Process::GO:0098656], [process, Biological Process::GO:0015849], [process, Biological Process::GO:0071705]
[molecular function, Molecular Function::GO:0015075], [molecular function, Molecular Function::GO:0046943], [molecular function, Molecular Function::GO:0022891], [molecular function, Molecular Function::GO:0022804], [molecular function, Molecular Function::GO:0046873]
[location, Cellular Component::GO:0031253], [location, Cellular Component::GO:0005903], [location, Cellular Component::GO:0098590], [location, Cellular Component::GO:0031526], [location, Cellular Component::GO:0098862]
Answer:
|
- Valganciclovir
- L-Proline
- Valaciclovir
|
Predict drugs for the central gene based on its neighborhood:
Central node: HRH3
One-hop neighbors: [process, Biological Process::GO:0007188], [process, Biological Process::GO:0007207], [process, Biological Process::GO:0046903], [process, Biological Process::GO:0007197], [process, Biological Process::GO:0007213]
[molecular function, Molecular Function::GO:0015464], [molecular function, Molecular Function::GO:0099528], [molecular function, Molecular Function::GO:0016907], [molecular function, Molecular Function::GO:0004930], [molecular function, Molecular Function::GO:0030594]
[location, Cellular Component::GO:0045202]
Answer:
|
- Betahistine
- Histamine Phosphate
- Decamethonium
- Clozapine
- Donepezil
- Mirtazapine
- Azelastine
|
Predict drugs for the central gene based on its neighborhood:
Central node: RDH13
One-hop neighbors: [process, Biological Process::GO:0048593], [process, Biological Process::GO:0001754], [process, Biological Process::GO:0009642], [process, Biological Process::GO:0048646], [process, Biological Process::GO:0046530]
[molecular function, Molecular Function::GO:0016491]
[location, Cellular Component::GO:0005743], [location, Cellular Component::GO:0005740], [location, Cellular Component::GO:0031966], [location, Cellular Component::GO:0019866]
Answer:
|
- Vitamin A
|
Predict drugs for the central gene based on its neighborhood:
Central node: SCN11A
One-hop neighbors: [process, Biological Process::GO:0001508], [process, Biological Process::GO:0098662], [process, Biological Process::GO:0019228], [process, Biological Process::GO:0043269], [process, Biological Process::GO:0015672]
[molecular function, Molecular Function::GO:0005261], [molecular function, Molecular Function::GO:0022890], [molecular function, Molecular Function::GO:0015081], [molecular function, Molecular Function::GO:0015077], [molecular function, Molecular Function::GO:0015267]
[location, Cellular Component::GO:0034706], [location, Cellular Component::GO:0030424], [location, Cellular Component::GO:1902495], [location, Cellular Component::GO:0034702], [location, Cellular Component::GO:0044299]
Answer:
|
- Benzocaine
- Procainamide
- Tocainide
- Ethotoin
- Zonisamide
- Cocaine
- Phenazopyridine
- Rufinamide
|
Predict drugs for the central gene based on its neighborhood:
Central node: L3HYPDH
One-hop neighbors: [molecular function, Molecular Function::GO:0016835], [molecular function, Molecular Function::GO:0016829], [molecular function, Molecular Function::GO:0016836]
Answer:
|
- L-Proline
|
Predict drugs for the central gene based on its neighborhood:
Central node: SLC46A1
One-hop neighbors: [process, Biological Process::GO:0006767], [process, Biological Process::GO:0019752], [process, Biological Process::GO:0055065], [process, Biological Process::GO:0006766], [process, Biological Process::GO:0006575]
[molecular function, Molecular Function::GO:0022891], [molecular function, Molecular Function::GO:0015075], [molecular function, Molecular Function::GO:0008324], [molecular function, Molecular Function::GO:0015350], [molecular function, Molecular Function::GO:0072341]
[location, Cellular Component::GO:0009986], [location, Cellular Component::GO:0031253], [location, Cellular Component::GO:0005903], [location, Cellular Component::GO:0098862], [location, Cellular Component::GO:0031526]
Answer:
|
- Methotrexate
- Pemetrexed
- Folic Acid
- Sulfasalazine
|
Predict drugs for the central gene based on its neighborhood:
Central node: STK38
One-hop neighbors: [process, Biological Process::GO:0031400], [process, Biological Process::GO:0018105], [process, Biological Process::GO:0051348], [process, Biological Process::GO:0071900], [process, Biological Process::GO:0010563]
[molecular function, Molecular Function::GO:0016772], [molecular function, Molecular Function::GO:0019900], [molecular function, Molecular Function::GO:0031435], [molecular function, Molecular Function::GO:0019901], [molecular function, Molecular Function::GO:0016773]
[location, Cellular Component::GO:0035097], [location, Cellular Component::GO:0070688], [location, Cellular Component::GO:1990234], [location, Cellular Component::GO:0034708]
Answer:
|
- Sunitinib
|
Predict drugs for the central gene based on its neighborhood:
Central node: AZIN2
One-hop neighbors: [process, Biological Process::GO:0019953], [process, Biological Process::GO:0006595], [process, Biological Process::GO:0033387], [process, Biological Process::GO:0015672], [process, Biological Process::GO:1901162]
[molecular function, Molecular Function::GO:0022890], [molecular function, Molecular Function::GO:0008519], [molecular function, Molecular Function::GO:0015075], [molecular function, Molecular Function::GO:0008047], [molecular function, Molecular Function::GO:0042978]
[location, Cellular Component::GO:0031984], [location, Cellular Component::GO:0043025], [location, Cellular Component::GO:0036477], [location, Cellular Component::GO:0005802], [location, Cellular Component::GO:0043005]
Answer:
|
- L-Arginine
|
Predict drugs for the central gene based on its neighborhood:
Central node: CHRNA3
One-hop neighbors: [process, Biological Process::GO:0043623], [process, Biological Process::GO:0014056], [process, Biological Process::GO:0007268], [process, Biological Process::GO:0045859], [process, Biological Process::GO:0007267]
[molecular function, Molecular Function::GO:0022891], [molecular function, Molecular Function::GO:0005261], [molecular function, Molecular Function::GO:0022857], [molecular function, Molecular Function::GO:0004889], [molecular function, Molecular Function::GO:0008144]
[location, Cellular Component::GO:0043005], [location, Cellular Component::GO:0044297], [location, Cellular Component::GO:0005892], [location, Cellular Component::GO:1990351], [location, Cellular Component::GO:0030425]
Answer:
|
- Dextromethorphan
- Bupropion
- Varenicline
- Levomethadyl Acetate
- Galantamine
- Pentolinium
- Cytisine
- Trimethaphan
- Mecamylamine
- Nicotine
|
Predict drugs for the central gene based on its neighborhood:
Central node: CHRNA5
One-hop neighbors: [process, Biological Process::GO:0010243], [process, Biological Process::GO:0098655], [process, Biological Process::GO:0007267], [process, Biological Process::GO:0007268], [process, Biological Process::GO:0030534]
[molecular function, Molecular Function::GO:0005216], [molecular function, Molecular Function::GO:0015075], [molecular function, Molecular Function::GO:0005261], [molecular function, Molecular Function::GO:0022891], [molecular function, Molecular Function::GO:0004889]
[location, Cellular Component::GO:0045211], [location, Cellular Component::GO:0098590], [location, Cellular Component::GO:1902495], [location, Cellular Component::GO:0098797], [location, Cellular Component::GO:0043005]
Answer:
|
- Nicotine
- Galantamine
|
Predict drugs for the central gene based on its neighborhood:
Central node: CHRNB2
One-hop neighbors: [process, Biological Process::GO:1903793], [process, Biological Process::GO:0000904], [process, Biological Process::GO:0042220], [process, Biological Process::GO:0007420], [process, Biological Process::GO:0048812]
[molecular function, Molecular Function::GO:0022838], [molecular function, Molecular Function::GO:0004889], [molecular function, Molecular Function::GO:0050997], [molecular function, Molecular Function::GO:0042166], [molecular function, Molecular Function::GO:0022836]
[location, Cellular Component::GO:0098802], [location, Cellular Component::GO:0097060], [location, Cellular Component::GO:1902495], [location, Cellular Component::GO:0009986], [location, Cellular Component::GO:0045202]
Answer:
|
- Nicotine
- Galantamine
- Varenicline
- Dextromethorphan
|
Predict drugs for the central gene based on its neighborhood:
Central node: CHRNB3
One-hop neighbors: [process, Biological Process::GO:0007268], [process, Biological Process::GO:0043279], [process, Biological Process::GO:0099537], [process, Biological Process::GO:0051259], [process, Biological Process::GO:0034220]
[molecular function, Molecular Function::GO:0015267], [molecular function, Molecular Function::GO:0005261], [molecular function, Molecular Function::GO:0008144], [molecular function, Molecular Function::GO:0022838], [molecular function, Molecular Function::GO:0004889]
[location, Cellular Component::GO:0045211], [location, Cellular Component::GO:0098590], [location, Cellular Component::GO:0097060], [location, Cellular Component::GO:0098802], [location, Cellular Component::GO:1990351]
Answer:
|
- Galantamine
- Nicotine
|
Predict drugs for the central gene based on its neighborhood:
Central node: CHRNB4
One-hop neighbors: [process, Biological Process::GO:0060073], [process, Biological Process::GO:0060084], [process, Biological Process::GO:0044057], [process, Biological Process::GO:0099565], [process, Biological Process::GO:0006939]
[molecular function, Molecular Function::GO:0005231], [molecular function, Molecular Function::GO:0022891], [molecular function, Molecular Function::GO:0015075], [molecular function, Molecular Function::GO:0004889], [molecular function, Molecular Function::GO:0008144]
[location, Cellular Component::GO:0098794], [location, Cellular Component::GO:0005892], [location, Cellular Component::GO:0098802], [location, Cellular Component::GO:0043005], [location, Cellular Component::GO:0098797]
Answer:
|
- Trimethaphan
- Nicotine
- Pentolinium
- Cytisine
- Levomethadyl Acetate
- Mecamylamine
- Dextromethorphan
- Galantamine
|
Predict drugs for the central gene based on its neighborhood:
Central node: CHRNE
One-hop neighbors: [process, Biological Process::GO:0006812], [process, Biological Process::GO:0003012], [process, Biological Process::GO:0050881], [process, Biological Process::GO:0014070], [process, Biological Process::GO:0035094]
[molecular function, Molecular Function::GO:0022857], [molecular function, Molecular Function::GO:0015267], [molecular function, Molecular Function::GO:0008324], [molecular function, Molecular Function::GO:0015464], [molecular function, Molecular Function::GO:0005230]
[location, Cellular Component::GO:0098794], [location, Cellular Component::GO:0098797], [location, Cellular Component::GO:0098802], [location, Cellular Component::GO:0005892], [location, Cellular Component::GO:0098796]
Answer:
|
- Decamethonium
- Galantamine
- Succinylcholine
|
Predict drugs for the central gene based on its neighborhood:
Central node: CHRNG
One-hop neighbors: [process, Biological Process::GO:0010243], [process, Biological Process::GO:0007267], [process, Biological Process::GO:0035094], [process, Biological Process::GO:0014070], [process, Biological Process::GO:0042391]
[molecular function, Molecular Function::GO:0030594], [molecular function, Molecular Function::GO:0008324], [molecular function, Molecular Function::GO:0070405], [molecular function, Molecular Function::GO:0022857], [molecular function, Molecular Function::GO:0005231]
[location, Cellular Component::GO:0005892], [location, Cellular Component::GO:0097060], [location, Cellular Component::GO:0098802], [location, Cellular Component::GO:0045211], [location, Cellular Component::GO:0034702]
Answer:
|
- Decamethonium
- Succinylcholine
- Galantamine
|
Predict drugs for the central gene based on its neighborhood:
Central node: CHUK
One-hop neighbors: [process, Biological Process::GO:0000165], [process, Biological Process::GO:0050776], [process, Biological Process::GO:0042476], [process, Biological Process::GO:0045088], [process, Biological Process::GO:0002573]
[molecular function, Molecular Function::GO:0016773], [molecular function, Molecular Function::GO:0046982], [molecular function, Molecular Function::GO:0097110], [molecular function, Molecular Function::GO:0016301], [molecular function, Molecular Function::GO:0016772]
[location, Cellular Component::GO:0098802], [location, Cellular Component::GO:0098552], [location, Cellular Component::GO:0035631], [location, Cellular Component::GO:0043235], [location, Cellular Component::GO:0098796]
Answer:
|
- Aminosalicylic Acid
- Sulfasalazine
- Mesalazine
- Acetylcysteine
|
Predict drugs for the central gene based on its neighborhood:
Central node: CKB
One-hop neighbors: [process, Biological Process::GO:0019752], [process, Biological Process::GO:0007417], [process, Biological Process::GO:0060322], [process, Biological Process::GO:0006576], [process, Biological Process::GO:0044106]
[molecular function, Molecular Function::GO:0031625], [molecular function, Molecular Function::GO:0044389], [molecular function, Molecular Function::GO:0016772], [molecular function, Molecular Function::GO:0004111], [molecular function, Molecular Function::GO:0016301]
[location, Cellular Component::GO:0043209]
Answer:
|
- Creatine
|
Predict drugs for the central gene based on its neighborhood:
Central node: SLC5A11
One-hop neighbors: [process, Biological Process::GO:0008643], [process, Biological Process::GO:0006812], [process, Biological Process::GO:0006814], [process, Biological Process::GO:0030001], [process, Biological Process::GO:0015672]
[molecular function, Molecular Function::GO:0022804], [molecular function, Molecular Function::GO:0015291], [molecular function, Molecular Function::GO:0015293], [molecular function, Molecular Function::GO:0022857]
Answer:
|
- Dapagliflozin
|
Predict drugs for the central gene based on its neighborhood:
Central node: CKM
One-hop neighbors: [process, Biological Process::GO:0006600], [process, Biological Process::GO:0006576], [process, Biological Process::GO:0044106], [process, Biological Process::GO:0006575], [process, Biological Process::GO:0042398]
[molecular function, Molecular Function::GO:0016772], [molecular function, Molecular Function::GO:0016301], [molecular function, Molecular Function::GO:0016775], [molecular function, Molecular Function::GO:0004111]
Answer:
|
- Creatine
|
Predict drugs for the central gene based on its neighborhood:
Central node: CKMT1B
One-hop neighbors: [process, Biological Process::GO:0006576], [process, Biological Process::GO:0006520], [process, Biological Process::GO:1901605], [process, Biological Process::GO:0006600], [process, Biological Process::GO:0006575]
[molecular function, Molecular Function::GO:0016775], [molecular function, Molecular Function::GO:0004111], [molecular function, Molecular Function::GO:0016772], [molecular function, Molecular Function::GO:0016301]
[location, Cellular Component::GO:0005740], [location, Cellular Component::GO:0005743], [location, Cellular Component::GO:0031966], [location, Cellular Component::GO:0019866]
Answer:
|
- Creatine
|
Predict drugs for the central gene based on its neighborhood:
Central node: CKMT2
One-hop neighbors: [process, Biological Process::GO:0006936], [process, Biological Process::GO:0006576], [process, Biological Process::GO:0006595], [process, Biological Process::GO:0009308], [process, Biological Process::GO:0006600]
[molecular function, Molecular Function::GO:0004111], [molecular function, Molecular Function::GO:0016772], [molecular function, Molecular Function::GO:0016775], [molecular function, Molecular Function::GO:0016301]
[location, Cellular Component::GO:0019866], [location, Cellular Component::GO:0031966], [location, Cellular Component::GO:0005743], [location, Cellular Component::GO:0005740]
Answer:
|
- Creatine
|
Predict drugs for the central gene based on its neighborhood:
Central node: SLC22A12
One-hop neighbors: [process, Biological Process::GO:0098656], [process, Biological Process::GO:0015747], [process, Biological Process::GO:0071705], [process, Biological Process::GO:0046415], [process, Biological Process::GO:0015711]
[molecular function, Molecular Function::GO:0015297], [molecular function, Molecular Function::GO:0015347], [molecular function, Molecular Function::GO:0015291], [molecular function, Molecular Function::GO:0015075], [molecular function, Molecular Function::GO:0022857]
[location, Cellular Component::GO:0098590], [location, Cellular Component::GO:0045177], [location, Cellular Component::GO:0005903], [location, Cellular Component::GO:0098862], [location, Cellular Component::GO:0031526]
Answer:
|
- Losartan
- Probenecid
- Sulfinpyrazone
|
Predict drugs for the central gene based on its neighborhood:
Central node: TGM7
One-hop neighbors: [process, Biological Process::GO:0018149]
[molecular function, Molecular Function::GO:0016755], [molecular function, Molecular Function::GO:0016746], [molecular function, Molecular Function::GO:0003810]
Answer:
|
- L-Glutamine
|
Predict drugs for the central gene based on its neighborhood:
Central node: RBP7
One-hop neighbors: [molecular function, Molecular Function::GO:0005501], [molecular function, Molecular Function::GO:0008289], [molecular function, Molecular Function::GO:0019841], [molecular function, Molecular Function::GO:0016918], [molecular function, Molecular Function::GO:0019840]
Answer:
|
- Vitamin A
|
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